Index Catalog // ScholarsArchive@OSU

The role of sigma factors in production of cyanobacterial natural products: Escherichia coli as a heterologous expression host

Creator:: Wells, Kaitlyn N.
Abstract:: Cyanobacteria represent an underexploited source of bioactive natural products of interest to the pharmaceutical industry. Lack of development of these compounds as drug leads is due mainly to myriad practical problems with the producing strains including long doubling times, genetic intractability, and low compound yields. Previous attempts at heterologous expression...
Resource Type:: Honors College Thesis
Full Text:: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 8 ACKNOWLEDGEMENTS To my mentor and advisor, Dr. Benjamin Philmus, I extend my

Aiding Plants and Humans by Targeting Virulence Strategies: Investigation of key protein residues involved in toxoflavin production

Creator:: Justen, Savannah F.
Abstract:: Toxoflavin, a toxic secondary metabolite produced by a variety of bacteria, has been implicated as a causative agent in food poisoning and a virulence factor in phytopathogenic bacteria. This toxin is produced by the tox operon in Burkholderia glumae, in which the encoded protein, ToxD, was previously characterized as essential...
Resource Type:: Honors College Thesis
Full Text:: approved: Benjamin Philmus Toxoflavin, a toxic secondary metabolite produced by a variety of bacteria

An Analysis of Surveys to Determine the Effectiveness of Bias in Question Wording as a Method of Skewing Reported Opinions

Creator:: Sharkansky, Benjamin I.
Abstract:: Clear and unbiased question wording is important to obtaining consistent and accurate survey results. However, if the goal is not to obtain accurate results but instead to obtain a specific result, then altering question wording may be effective. To examine this possibility, we created a survey with 9 different versions...
Resource Type:: Honors College Thesis
Full Text:: Question Wording as a Method of Skewing Reported Opinions. by Benjamin Sharkansky A THESIS submitted to

Analysis of SNPs in Mycoplasma cynos strains from canine hosts within the Pacific Coast animal shelter network

Creator:: Prymolenna, Anastasiya V.
Abstract:: Single nucleotide polymorphisms (SNPs) can be used as markers to infer population genetic structure. For Mycoplasma cynos, a pathogen associated with infectious respiratory disease among canines and other animals, SNPs may help to elucidate ecological and evolutionary relationships among the strains that reside in the upper respiratory tract of canines...
Resource Type:: Honors College Thesis
Full Text:: :_____________________________________________________ Benjamin Dalziel Single nucleotide polymorphisms (SNPs) can be used as markers to infer

Consistent Histories Formulation of the Double-Slit Experiment

Creator:: Bauml, Benjamin N.
Abstract:: The standard interpretation of quantum mechanics (known as the Copenhagen interpretation) divides the world into quantum phenomena and classical observers that perform measurements upon the phenomena. This provides a quite functional framework for calculating probabilities of measurement outcomes, but it lacks the generality necessary for such things as retrodiction, and...
Resource Type:: Honors College Thesis
Full Text:: by Benjamin Noë Bauml A THESIS submitted to Oregon State University Honors College in partial

Genetic and morphological evidence suggests cryptic speciation within the Torrent Sculpin, Cottus rhotheus, across the Pacific Northwest

Creator:: Nicholas, Benjamin P.
Abstract:: Dwelling on the bottom of large rivers to high alpine streams, freshwater sculpins (genus Cottus) occur in high densities across the Pacific Northwest, with 21 currently recognized species found in the Pacific Northwest. Sculpin fill many ecological roles, with some species serving as important prey sources, and others competing with...
Resource Type:: Honors College Thesis
Full Text:: speciation within the Torrent Sculpin, Cottus rhotheus, across the Pacific Northwest by Benjamin

Characterizing the Interaction between BCL11B and TCF-1 transcription factors in the control of the BCL-xL gene

Creator:: Nagra, Alamjit K.
Abstract:: Immature T cells, known as thymocytes, undergo development through successive stages in the thymus and the periphery to become functional mature T cells. These stages are regulated by sequence specific transcription factors (SSTFs). Two such SSTFs, BCL11B and TCF-1, are both known master regulators of thymopoiesis, which is also known...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Benjamin Philmus, Committee Member, representing Pharmaceutical Sciences

Stress and Learning in Larval Zebrafish (Danio rerio)

Creator:: Moussaoui, Bushra
Abstract:: In this study, we characterize the behavioral response of larval zebrafish (Danio rerio) to the noxious chemical allyl isothiocyanate (AITC), an agonist of the nociceptive TRPA1 ion channel, and utilize AITC as an aversive stimulus in an associative learning paradigm. We find that larvae exposed to AITC in both a...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Benjamin Dalziel, Committee Member, representing Department of Integrative Biology

Isolation and Identification of Indole Metabolites from Pseudomonas fluorescens NZI7

Creator:: Vergis, John M.
Abstract:: Pseudomonas fluorescens NZI7 was first isolated from a New Zealand mushroom farm in 2001. This Gram-negative bacteria can cause brown blotch disease in the basidiomycete mushroom Agaricus bisporus. P. fluorescens NZI7 can also repel grazing by the nematode Caenorhabditis elegans, a natural predator of P. fluorescens NZI7. Potentially implicated in...
Resource Type:: Honors College Thesis
Full Text:: ______________________________________________________________ Benjamin Philmus, Committee Member, representing Pharmaceutical Sciences

Second Derivative Excitation Emission Resolution (SEC DEER) Spectroscopy

Creator:: Rosene, Benjamin L.
Abstract:: Fluorescence spectroscopy is a powerful analytical technique due to bright signals that provide excellent measurement sensitivity. Many colors of fluorescent dyes are available to match the detection ranges of different equipments. Dyes can be chemically modified to bind to many different target analytes with high specificity1. Alternatively, sensors can be...
Resource Type:: Honors College Thesis
Full Text:: ) Spectroscopy by Benjamin L. Rosene A THESIS submitted to Oregon

ScholarsArchive@OSU

The role of sigma factors in production of cyanobacterial natural products: Escherichia coli as a heterologous expression host

Aiding Plants and Humans by Targeting Virulence Strategies: Investigation of key protein residues involved in toxoflavin production

An Analysis of Surveys to Determine the Effectiveness of Bias in Question Wording as a Method of Skewing Reported Opinions

Analysis of SNPs in Mycoplasma cynos strains from canine hosts within the Pacific Coast animal shelter network

Consistent Histories Formulation of the Double-Slit Experiment

Genetic and morphological evidence suggests cryptic speciation within the Torrent Sculpin, Cottus rhotheus, across the Pacific Northwest

Characterizing the Interaction between BCL11B and TCF-1 transcription factors in the control of the BCL-xL gene

Stress and Learning in Larval Zebrafish (Danio rerio)

Isolation and Identification of Indole Metabolites from Pseudomonas fluorescens NZI7

Second Derivative Excitation Emission Resolution (SEC DEER) Spectroscopy

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