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Filtering by: Creator Brink, Susan E. Degree Name Honors Bachelor of Science (H.B.S.)

Gene-specific antibiotic development: Evaluating effectiveness and investigating antibiotic-resistant Escherichia coli mutants of phosphorodiamidate morpholino oligomers

Creator:

Puckett, Susan E.

Abstract:

Phosphorodiamidate morpholino oligomers (PMOs) are novel antisense drugs in the early stages of development. These synthetic DNA mimics contain the same bases found in DNA and anneal to RNA in a complementary fashion. PMOs have been designed that target genes responsible for producing essential proteins in organisms such as Escherichia...

Resource Type:

Honors College Thesis

Full Text:

phosphorodiamidate morpholino oligomers by Susan E. Puckett A PROJECT submitted to Oregon State University