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  • Mathematical Investigation of Evaporation Synergy in Bi-Texture Soil Columns as a Function of Column Width

    Creator:
    Sumner, Michael J.
    Abstract:
    Evaporation synergy is a phenomenon that occurs between different classes of soil and allows for a greater amount/quantity of soil water evaporation. 20 of the 66 soil texture class combinations have been shown to exhibit evaporation synergy (Fisher, 2012), however the impact of column width on the functionality of this...
    Resource Type:
    Honors College Thesis
    Full Text:
    Approved: Maria Dragila       Evaporation synergy is a phenomenon that occurs between different

  • The Effect of Protein Nitration on Cell Survival Pathways in Schwann Cells

    Creator:
    Graumann, Oliver W.
    Abstract:
    Neurofibromatosis type 2 (NF2) is a genetic disorder caused by the inactivation of the merlin tumor suppressor gene. NF2 patients develop bilateral vestibular schwannomas (VS) and other nervous system tumors with no effective drug treatment option. In pathological conditions, including NF2, production of the oxidant peroxynitrite leads to protein tyrosine...
    Resource Type:
    Honors College Thesis
    Full Text:
    Maria C. Franco Neurofibromatosis type 2 (NF2) is a genetic disorder caused by the

  • Role of Nitrated Hsp90 in Schwannoma Cell Survival

    Creator:
    Kim, Sharon R.
    Abstract:
    Neurofibromatosis Type 2 (NF2) is a genetic tumor disorder caused by mutations that inactivate the gene coding for the Merlin tumor suppressor. Patients with NF2 develop multiple tumors throughout the nervous system, mainly schwannomas, for which there is no cure or effective treatment. In NF2, redox signaling and oxidative stress...
    Resource Type:
    Honors College Thesis
    Full Text:
    approved:_____________________________________________________ Maria C. Franco Neurofibromatosis

  • Regulation of the Metabolic Reprogramming of Schwannoma Cells by Nitrated Hsp90

    Creator:
    Bastian, Lydia P.
    Abstract:
    This work is concerned with determining whether nicotine has a role in promoting oxidative damage in human tissue, particularly in lung tissue. This follows from recent reports of a novel lung disease found in some E-cigarette users, characterized by oxidative damage and elevated levels of neutrophils (termed “vaping disease”). It...
    Resource Type:
    Honors College Thesis
    Full Text:
    :_____________________________________________________ Maria Clara Franco Neurofibromatosis type 2 (NF2) is a genetic tumor disorder that

  • Investigating physical drivers of phytoplankton bloom initiation in the Northern Gulf of Alaska

    Creator:
    Ballantine, Kaleigh
    Abstract:
    The spring bloom is a key oceanic phenomenon in the Northern Gulf of Alaska (NGA), where it supports the regional ecosystem, fisheries, and CO2 sequestration. Despite its significance, mechanisms that trigger NGA blooms are still debated, largely due to a lack of sufficient data from late winter through spring. New...
    Resource Type:
    Honors College Thesis
    Full Text:
    :_____________________________________________________ Maria Kavanaugh Abstract approved:_____________________________________________________

  • Marine Nitrogen Subsidies to Terrestrial Systems: Transport Through Wrack Deposition

    Creator:
    Traylor, Andrew
    Abstract:
    Fluctuations in one system affect adjacent systems; mechanistic understanding of linkages helps conservation efforts be more effective by focusing on influential species and areas that facilitate connections between ecosystems. This study explored marine-derived nutrient inputs to adjacent terrestrial communities. We quantified wrack (seaweed and other organic matter) deposition at sites...
    Resource Type:
    Honors College Thesis
    Full Text:
    ______________________________________________________________________________ Committee Member: Maria Kavanaugh, representing Oceanography

  • The Tradition of Wind Band Music in Hawaii : The Hawaii County Band

    Creator:
    D'Angelo, Maria Grace
    Abstract:
    The Hawai’i County Band is based in Hilo, Hawai’i and was founded in 1883 by brothers Joaquin and Jules Carvalho. After the Kingdom of Hawai’i was overthrown in 1893, the band became known as the Hilo Portuguese Band and after the United States made Hawai’i a territory, the band became...
    Resource Type:
    Honors College Thesis
    Full Text:
    year playing with the band. We played a medley from the Wizard of Oz and I watched Mr. Ikeda play the

  • Analysis of Convolutional Neural Network Image Pre-processing Methods

    Creator:
    Jacobsen, Matthew
    Abstract:
    Oceanic plankton have both a large impact on our oceans health and atmo- spheric balance of Co2. The overall health of planktonic life is determined by many physical, chemical, and ecological factors, that drive taxonomic abundances and the relative amount of non-living biomass called detritus. Recent advances in microscopic imaging...
    Resource Type:
    Honors College Thesis
    Full Text:
    , representing Electrical Engineering and Computer Science Maria Kavanaugh, Committee Member, representing Earth

  • Addressing ALS: Corroborating the Methodology of Studying the P2X7R Complex

    Creator:
    Veytsman, Edward Y.
    Abstract:
    Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of motor neurons in the motor cortex and spinal cord. Recent evidence suggests that the purine receptor P2X7 (P2X7R) plays a central role in the pathology of ALS. Previous research indicates that P2X7R activation by oxidatively modified heat shock protein 90...
    Resource Type:
    Honors College Thesis
    Full Text:
    . Mol Ther Methods Clin Dev. 3, 15055 31.​. Marchetto, M. C. N., Muotri, A. R., Mu, Y., Smith, A. M

  • Metabolic Analysis of Bovine Nucleus Pulposus Cells with Constant and Variable Glucose Supply

    Creator:
    Rosene, Rees Alan
    Abstract:
    There is no standardized method for culture of intervertebral disc (IVD) cells when monitoring metabolic processes. We hypothesize that the metabolic rates of cells that are crucial to experiment designs depend on the cell culture method used. The glycolytic pathway and the tricarboxylic acid (TCA) cycle are the pathways through...
    Resource Type:
    Honors College Thesis
    Full Text:
    _____________________________________________________________________ Maria Franco, Committee Member, representing the School of Biochemistry and Biophysics