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Filtering by: Committee Member Burton, R. M. Remove constraint Committee Member: Burton, R. M. Degree Name Master of Science (M.S.) Remove constraint Degree Name: Master of Science (M.S.) Subject Antibiotics Remove constraint Subject: Antibiotics

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  • Biosynthetic studies of fungal diterpene antibiotics

    Creator:
    Yao, Qingmei
    Abstract:
    The isoprenoid pathway is one of the major biosynthetic pathways of secondary metabolites. Isoprenoids with a C₂₀ skeleton are known as diterpenoids and are derived from the common precursor, geranylgeranyl diphosphate (GGPP). This dissertation describes approaches to discover the diterpene synthase enzymes which provide the backbone structures for pleuromutilin and...
    Resource Type:
    Masters Thesis
    Full Text:
    willing to help whenever I encounter difficulties. I would like to thank Dr. Patricia M. Flatt. She gave