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Filtering by: Creator Lebleu, Bernard Degree Name Master of Science (M.S.)

The Role of Tumor-Derived Exosomes in the Development of Carboplatin Resistance in Canine Osteosarcoma

Creator:

Weinman, Marcus

Abstract:

Many humans and canines alike suffer from osteosarcoma, which is often metastatic, resistant to chemotherapy, and frequently fatal. The mechanisms through which osteosarcoma cells acquire resistance to chemotherapy are not entirely understood, and the role of exosomes as intercellular mediators of this resistance in osteosarcoma is unknown. Using established canine...

Resource Type:

Masters Thesis