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Creator:: Dille, Kenneth Leroy
Resource Type:: Masters Thesis
Full Text:: establishment of its structure, 4 One of the problem8 related to the preparation or nucleic acid is the

Creator:: Winzeler, Elizabeth A.
Abstract:: The effects of pH on the torsional flexibility of DNA bound to a nucleosome core particle were investigated by studying the time-resolved fluorescence anisotropy decays of ethidium bromide intercalated into the DNA of the core particle. As the torsional flexibility of DNA is affected by the presence of an intercalating...
Resource Type:: Masters Thesis
Full Text:: , periodically twisted around globular proteins in a linear array, is somehow coiled into the ordered structure

Creator:: Rinard, Gilbert Allen
Abstract:: The effects of estrogen treatment on uterine weight, uterine nucleic acid content and adrenal weight were studied. Daily doses of 0.05μg or 0.1 μg of Estradiol 17-β were administered subcutaneously to seven day castrated female rats for periods varying from 0 to 168 days. After two days of treatment uterine...
Resource Type:: Masters Thesis
Full Text:: of estrogen treatrnent on uterine weight, uterine nucleic acid content and adrenal weight were

Creator:: Baeuerle, Brigitte G.
Abstract:: Nucleic acid estimates in tissues of marine macrophytes with the fluorochromes Hoechst 33258 and ethidium homodimer were severely impaired by high concentrations of interfering compounds. The isolation and extraction techniques used pointed towards compounds of low molecular weight and of polar characteristics that were insensitive to organic solvent extraction and...
Resource Type:: Masters Thesis

Creator:: Yu, Yupei
Abstract:: Nalidixic acid and its derivatives act through inhibition of bacterial DNA gyrase activity. Recently there have been a series of papers reporting the antibacterial activity against three different types of bacteria (S. aureus, E. coli and P. aeruginosa) by a series of 1,4-dihydro-4-oxoquinoline (or 1,8-naphthyridine) 3-carboxylic acids. Consistent biological data...
Resource Type:: Masters Thesis
Full Text:: Relationships Study of Antiinfectives Based on the Nalidixic Acid Structure Redacted for privacy Abstract

Creator:: Kaller, Margo
Abstract:: Peptide-phosphorodiamidate morpholino oligomers (PPMOs) are synthetic DNA mimics that bind and silence gene targets. Through designing PPMOs that silence essential or resistance genes in pathogens, these antisense oligomers could be utilized as novel antimicrobials. Towards this end, my thesis employed minimum inhibitory concentration assays (MICs) to identify PPMOs capable of...
Resource Type:: Masters Thesis
Full Text:: Structure of Locked Nucleic Acid Antisense Oligomers……………….8 5. PNA versus DNA Scaffolds

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