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Pathogenic Mechanisms of Cancer Causing hMLH1 Mutations

Creator:

O'Donnell, Edmond Francis

Abstract:

DNA mismatch repair (MMR) is an evolutionary conserved process that functions to maintain genomic integrity through the correction of mismatches that have escaped proofreading. Mutations in the MMR gene Mlh1 are associated with approximately 50% of all cases of Lynch syndrome, a hereditary predisposition to colorectal cancer, through varying and...

Resource Type:

Honors College Thesis
The application of geographic information systems for delineation and classification of tidal wetlands for resource management of Oregon’s coastal watersheds

Creator:

Scranton, Russell W.

Abstract:

Resource managers of Oregon’s tidal wetlands require an improved GIS layer for management of existing tidal wetland habitat and areas considered for tidal wetland restoration. A reconnaissance project was initiated, such that interpretations of remote sensing data, the National Wetland Inventory, Oregon Estuary Plan Book and additional management tools were...

Resource Type:

Capstone Project