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  • Discovery and identification of antibacterial agents for dental use

    Creator:
    Kirkpatrick, Adam G.
    Abstract:
    Dental disease is a very prevalent and costly disease in which the symptoms, not the disease, are currently being treated. The disease is caused by pathogenic oral bacteria, many of which are a part of the Mutans Streptococci. The objective of this thesis was to find a natural substance that...
    Resource Type:
    Honors College Thesis
    Full Text:
    . (February 2003). 41(2), 657-666. 10. Kazlauskas, Rymantas; Murphy, Peter T.; Quinn, Ronald J.; Wells, Robert

  • Aging and oxidative damage to mitochondrial membrane proteins

    Creator:
    Tong, Tony T.
    Abstract:
    Mitochondria provide energy for biological cells to function, but this process is also a source of oxygen radicals that are capable of damaging nearby proteins. Mitochondrial protein damage can eventually lead to cell death, especially in the case of heart cells, where mitochondria are present in the highest concentrations. As...
    Resource Type:
    Honors College Thesis
    Full Text:
    . Fohlman, Biomed Mass Spectrom, 1984, 11, 601. 11. R. S. Johnson, S. A. Martin, K. Biemann, J. T. Stults

  • Prey swimming behavior and culture techniques for copper, Sebastes caurinus, and quillback rockfish, S. malinger

    Creator:
    Gilbert, Thom H.
    Abstract:
    Rotifers and brine shrimp (Artemia) are important prey items for rearing marine fish larvae. Their availability in the water column may be reduced when they are transferred to larval rearing tanks at lower temperature. In this study, Brachionus rotundiformis (SS-type) and Brachionus plicatilis (L-type) were semi-continuously cultured and fed on...
    Resource Type:
    Masters Thesis

  • A genomic and proteomic characterization of the first cultured oligotrophic marine Gammaproteobacterium from the SAR92 clade

    Creator:
    Mellbye, Brett L.
    Abstract:
    High-throughput culturing (HTC) consisting of extinction culturing in autoclaved seawater has led to the isolation and characterization of many novel strains of oligotrophic marine bacteria. Strain HTCC 2207 was isolated from the Oregon coast by the HTC method. Phylogenetic analysis based on 16S rRNA gene sequence showed that this strain...
    Resource Type:
    Honors College Thesis
    Full Text:
    Biochemical Tests. J Clinical Microbiol. 37: 2255-2261. Kaeberlein, T., K. Lewis, and S.S. Epstein. 2002

  • Perceptual thresholds for foot slipping in animated characters

    Creator:
    Strawn, Jordan J.
    Abstract:
    The computer game industry continues to progress toward realistic-looking character motion. However, even in state-of-the-art games, the use of motion capture data in character animation may result in errors such as “foot slipping,” where the feet do not match up with the floor properly during translation. Various algorithms have been...
    Resource Type:
    Honors College Thesis
    Full Text:
    Slipping in Animated Characters by Jordan J. Strawn A PROJECT submitted to Oregon State University

  • A bibliotherapy evaluation tool: grounding counselors in the therapeutic use of literature

    Creator:
    Pehrsson, Dale Elizabeth and McMillen, Paula S.
    Abstract:
    Discusses the development and evolution of the Bibliotherapy Evaluation Tool to help graduate counseling students use literature in therapy ethically and appropriately. A survey of bibliotherapeutic practice in the helping professions is provided. Graduate students showed greater knowledge of and comfort with bibliotherapy after exposure to a teaching module and...
    Resource Type:
    Article and Preprint
    Full Text:
    -Review, 22(2), 36-40. Pardeck, J. T. (1990). Bibliotherapy with abused children. Families in Society, 71

  • Entrapment of Micro-Algae in Modified Alginate Beads for Oxygen and Nutrient Source

    Creator:
    Hughson, Jason D.
    Abstract:
    Presented here is an investigation and comparison of two entrapment methods of algae. Conventional calcium alginate bead entrapment is compared to a recently described modified bead entrapment method, utilizing poly(ethylene glycol) and calcium alginate, which results in void or capillary formation within the beads. It is shown that algal growth...
    Resource Type:
    Honors College Thesis
    Full Text:
    . Statistical analysis, a Student’s t-test, utilizing Microsoft Excel was done on growth rates (Appendix C

  • Pathogenic Mechanisms of Cancer Causing hMLH1 Mutations

    Creator:
    O'Donnell, Edmond Francis
    Abstract:
    DNA mismatch repair (MMR) is an evolutionary conserved process that functions to maintain genomic integrity through the correction of mismatches that have escaped proofreading. Mutations in the MMR gene Mlh1 are associated with approximately 50% of all cases of Lynch syndrome, a hereditary predisposition to colorectal cancer, through varying and...
    Resource Type:
    Honors College Thesis
    Full Text:
    containing either a synthetic G/T mismatch or CT-loop were constructed as previously described (40), with

  • Investigating the Role of the MutLα Endonuclease

    Creator:
    Mankaney, Gautam Naresh
    Abstract:
    Lynch individuals have a predisposition to developing colorectal and other cancers due to inherited defects in their mismatch repair (MMR) system. Although mutations in MMR have been directly implicated in Lynch Syndrome, the precise mechanism(s) of MMR functions have yet to be elucidated. One essential complex, MutL (a dimer of...
    Resource Type:
    Honors College Thesis
    Full Text:
    provided by Dr. John B. Hays (Dept. of Mol. Tox., Oregon State University). pRO1 with a G/T mismatch and 3

  • Investigation of the roles of viral proteinases in the vaccinia virus life cycle

    Creator:
    Page, Jessica M.
    Abstract:
    An inducible, mutant virus, designated vvtetO:I7L/G1L, was used to study the morphogenic proteolysis step of the vaccinia virus life cycle. The vvtetO:I7L/G1L controlled the expression of two genes, I7L, a cysteine proteinase, and G1L, a putative metalloproteinase. These proteins are involved in the maturation of viral core proteins, p4a, p4b,...
    Resource Type:
    Honors College Thesis
    Full Text:
    , cells that constitutively express the tetracycline repressor must be used. T-REx 293 cells (Invitrogen