Chlamydiae are obligate intracellular bacteria that infect a variety of
eukaryotic hosts and affect normal host processes. Within host cells, their
developmental cycle takes place inside non-acidified vacuoles termed inclusions. An
inclusion membrane composed primarily of secreted chlamydial synthesized proteins
called Incs encloses the inclusion. At this location, Incs have...
Tetracycline (Tet)-resistant strains of Chlamydia suis were isolated from swine
farms in the Midwest. The isolation of the resistant strains was significant
because Tet is an antibiotic used to treat infections by veterinarians and
doctors. One of the tetracycline (Tet)-resistant strains, R19, was able to
survive in Tet up to...
The majority of our modern understanding of bacterial pathogenesis is based on the strategy that involves screening bacterial genomes for the presence of the genes encoding pathogenic factors, and analysis of these genes via forward and reverse genetics. Chlamydiae represent a unique group of pathogenic bacteria in which it is...