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Filtering by: Creator Hipkins, Valerie D. Remove constraint Creator: Hipkins, Valerie D. File Format application/pdf Remove constraint File Format: application/pdf Resource Type Dissertation Remove constraint Resource Type: Dissertation

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  • Transcriptional repression by CTIP2, a C2H2 zinc finger protein

    Creator:
    Topark-Ngarm, Acharawan Khamsiritrakul
    Abstract:
    CTIP2, a novel C2H2 zinc finger protein, is a transcriptional repressor that functions by at least two mechanisms. CTIP2 interacts with and stimulates transcriptional repression mediated by COUP-TF family members. CTIP2 also represses transcription independently of COUP-TF proteins by direct, sequence-specific DNA binding activity. CTIP2 has been implicated in lymphoid...
    Resource Type:
    Dissertation
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    , friendship, and encouragement, particularly Valerie Peterson, Olga Golonzhka, Lingjuan Zhang, Anand

  • Structural studies of the antioxidant defense enzymes; copper, zinc superoxide dismutase and alkyl hydroperoxide reductase flavoprotein

    Creator:
    Roberts, Blaine R.
    Abstract:
    Oxygen derived radicals are involved in many aspects of life from aging and cell signaling to disease states as diverse as heart disease, diabetes, neurodegeneration and inflammation. Therefore, understanding the function of antioxidant defense proteins and the effects of oxygen derived radicals on protein function is essential to elucidate the...
    Resource Type:
    Dissertation
    Full Text:
    . Tainer2*, Elizabeth D. Getzoff2, Dean A. Malencik1, Sonia R. Anderson, Valerie C. Bomben1, Kathrin R

  • Functional analysis of the biosynthetic gene cluster of the antitumor agent cetoniacytone A

    Creator:
    Wu, Xiumei
    Abstract:
    A gene cluster responsible for the biosynthesis of the antitumor agent cetoniacytone A was identified in Actinomyces sp. strain Lu 9419, an endosymbiotic bacteria isolated from the intestines of the rose chafer beetle. The nucleotide sequence analysis of the 26 Kb DNA region revealed the presence of 17 complete ORFs,...
    Resource Type:
    Dissertation
    Full Text:
    constructing and screening cosmid library. I am grateful to Valerie Peterson for showing me the HPLC working

  • How refrigeration, heating, ventilation, and air conditioning service technicians learn from troubleshooting

    Creator:
    Green, Denis F. H.
    Abstract:
    The purpose of this study was to understand how refrigeration, heating, ventilation, and air conditioning (RHVAC) service technicians (techs) learned from troubleshooting. This understanding resulted in instructional and curricular strategies designed to help community colleges prepare vocational students to learn more effectively from informal workplace learning. RHVAC techs were studied...
    Resource Type:
    Dissertation
    Full Text:
    Valerie Lau contributed greatly by acting as outside readers. Additional thanks to Sam Stern for

  • Geneticist L.C. Dunn : politics, activism, and community

    Creator:
    Gormley, Melinda (Melinda Brooke)
    Abstract:
    L. C. Dunn (1893-1974) spent most of his scientific career conducting research in developmental genetics as a member of the Zoology Department at Columbia University in the City of New York. He had an accomplished scientific career researching mutations in mice, which earned him respect from other geneticists and scientists....
    Resource Type:
    Dissertation
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    Ahern, Roy Goodman, and Valerie-Anne Lutz, was incredibly generous throughout my three months there