Under laboratory conditions, elevated temperatures accelerated production of gametes. However, when conditioning for spawning at elevated temperatures was
initiated early in the season (January-March), larval survival and number of spat collected were significantly lower than when conditioning was initiated in may or June. At elevated temperatures, broodstock oysters were fed...
This thesis details my investigation of some pharmaceuticals and natural products on the transport of drugs which are substrates of P-glycoprotein (P-gp), such as cyclosporin A (CSA) and digoxin by using Caco-2 and MDCKII-MDR1 drug transport models. Three objectives were performed to address this goal. The first objective was to...
The microbial loop plays a crucial role in remineralization of organic matter and fuels recycled production in the aquatic environment. The capability of microbes to utilize particular compounds can be examined through their ectoenzyme (found outside the cell) activities using fluorogenic substrate analogs. These catalysts hydrolyze polymers otherwise too large...
The objective of this research project was to increase the density, strength, and stiffness of two low to medium-density diffuse-porous hardwood species. Wood used in this study was processed using a method of wood densification known as “Viscoelastic Thermal Compression” (VTC). The VTC process is a three phase treatment which...
Island biogeography has strongly influenced the study of biodiversity because
archipelagos provide natural model systems for investigating patterns of diversity and the
processes that shape ecological communities. I investigated the influence of area and
isolation of islands (n = 32) in the Gulf of California, Mexico on patterns of richness,...
Marine sediments exceptionally rich in organic carbon, known as black shales, occur globally but intermittently in well correlated Cretaceous successions. The presence of black shales indicates that sporadic, ocean-wide interruption of normal respiration of marine organic matter during oxygen-deficient conditions has occurred. Submarine volcanism on a massive scale, related to...
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Robert A. Duncan
Marine sediments exceptionally rich in organic carbon, known as
Abstract Watershed-scale fate/transport modeling of contaminants is a tool that scientists and land managers can use to assess pesticide contamination to stream systems. The Catchment Modeling Framework (CMF) is a catchment-scale fate/transport modeling tool. It was developed to help scientists and land managers assess the effects of possible land-use decisions...
Studies toward the total syntheses of highly potent cytotoxic alkaloids
including the bromopyrrole alkaloids and indole alkaloids were conducted and are
described. Studies carried out in the course of this dissertation consist of five total syntheses of natural products that include bromopyrrole alkaloids nagelamide A, D and agelastatin D as...