The total synthesis of a highly potent cytotoxic marine natural product, phorboxazole A, is described. Both a palladium(II)-mediated and a palladium(II)-catalyzed intramolecular alkoxycarbonylation were used as key steps for the preparation of the two cis-2,6-disubstituted tetrahydropyran rings (C22-C26 and C11-C15) of phorboxazole A.
The synthesis used a convergent approach involving...
On the surface, the written works of the Marquis de Sade appear to be nothing more than pornographic mania articulated, the narrative trajectory of which oscillates between illicit words and acts. Yet his life and works are important to historians, if not due to their inherent quality then because they...
In this thesis, I conduct an analysis of blogs in order to understand their potential use in the composition classroom with the goals of students writing for a public audience and developing their rhetorical and civic agency. I do so by exploring the potential for the blogosphere as a public...
People often grow increasingly culturally confused when spending significant amounts of time in a foreign land. Identity can become lost only to reform in the image of the host society. This thesis presents a creative nonfiction series of essays that explore the author’s loss of self and contextual identity, the...
This phenomenological inquiry explored dimensions of reflection for older adults in a developmental oriented adventure education experience. Data were gathered from emergent interviews with four individuals while participating in a multi-day, self-contained experiential education program conducted in a rugged environment, and led by a Navajo leader. Two principle research questions...
The presence and significance of salmon for prehistoric and aboriginal people of the Columbia Plateau is a matter of considerable debate among anthropologists, archaeologists and historians. Data from over 100 archaeological sites are scrutinized in the light of an example salmon fishery developed from ethnographic and archaeological information on aboriginal...
Fifty-seven species of wildlife rely on or frequently use snags for breeding, roosting, or denning in Oregon and Washington. Several publications offer information on use of snags by wildlife, influence of management activities on snags and snag users, and approaches to managing snags to benefit wildlife. Because of the diverse...
In the United States, many of the thorniest natural resource conflicts occur on private lands. This is especially true in the Willamette Valley of Western Oregon where the hallmark habitat type, Oregon white oak woodland and savanna, is imperiled. Almost exclusively found on private land, Oregon white oak is threatened...
This thesis examines the nature of publishing as a political endeavor through a detailed investigation of the feminist publishing movement in the U.S. since the 1970s. Feminist publishers emerged from an activist context of feminist struggle, and they evolved within changing political and social climates, facing ideological and economic challenges...