The unfolding of human retinoid X receptor α in the presence of the denaturant guanidine HCl was studied using stopped-flow absorbance spectroscopy. The protein's four native cysteine residues were mutated to obtain four single-cysteine mutants, each with the other three cysteine residues mutated to alanine. The thiols of these hRXRα...
In rats, sesame lignans increase plasma γ-tocopherol concentrations and inhibit γ-tocopherol degradation to its metabolite γ-carboxyethylhydroxychroman (γ-CEHC). To test if sesame lignan consumption inhibits γ- tocopherol metabolism in humans, muffins prepared with either corn oil (control) or sesame oil and an equimolar mixture of deuterium labeled d6-α- and d2-γ- tocopheryl...
This report is one of a series issued in cooperation with the Army-Navy-Civil Committee on Aircraft Design Criteria under the supervision of the Aeronautical Board. Information reviewed and reaffirmed 1960.
This thesis contains three manuscripts addressing the application of stochastic processes to the analysis and solution of partial differential equations (PDEs) in mathematical physics.
In the first manuscript, one dimensional diffusion and Burgers equation are considered. The Fourier transform of the solution to each PDE is represented as the expected...
While the heartwood of many wood species exhibits excellent resistance to fungal and insect attack, this resistance is sometimes diminished in second-growth material of the same species. The reasons for the reduced durability are unclear, but they may reflect a combination of both higher proportions of sapwood as well as...
This research was designed to broaden the understanding of how timber-harvest affects aquatic macroinvertebrates in perennial and intermittent headwater streams. This study compared emergent and benthic macroinvertebrate assemblages from 20 headwater streams in the central Oregon Coast Range that varied by harvest condition and flow duration. Through comparison of the...
RNA silencing pathways are required for a wide variety of processes in most
eucaryotes. In plants, small-interfering RNA (siRNA) arising from transposons and other
repetitive sequences is associated with heterochromatin formation and maintenance.
MicroRNAs and trans-acting siRNAs encoded at discrete loci function as negative regulators of
gene expression by triggering...