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  • Characterization of the genomic islands from tetracycline-resistant Chlamydia suis

    Creator:
    Dugan, Jae
    Abstract:
    Tetracycline (Tet)-resistant strains of Chlamydia suis were isolated from swine farms in the Midwest. The isolation of the resistant strains was significant because Tet is an antibiotic used to treat infections by veterinarians and doctors. One of the tetracycline (Tet)-resistant strains, R19, was able to survive in Tet up to...
    Resource Type:
    Dissertation
    Full Text:
    , Mahfuz Sarker, Mark Zabriskie, Doug Barofsky, and Claudia Hase. Not only has Dennis Hruby and Mark

  • Functional analysis of the biosynthetic gene cluster of the antitumor agent cetoniacytone A

    Creator:
    Wu, Xiumei
    Abstract:
    A gene cluster responsible for the biosynthesis of the antitumor agent cetoniacytone A was identified in Actinomyces sp. strain Lu 9419, an endosymbiotic bacteria isolated from the intestines of the rose chafer beetle. The nucleotide sequence analysis of the 26 Kb DNA region revealed the presence of 17 complete ORFs,...
    Resource Type:
    Dissertation
    Full Text:
    system. I am indebted to my committee members, Dr. Mark Zabriskie, Dr. Mahfuz Sarker, Dr. Xihou

  • Analysis of chlamydial and host proteins associated with infection

    Creator:
    Chu, Hencelyn
    Abstract:
    Chlamydiae are obligate intracellular bacteria that infect a variety of eukaryotic hosts and affect normal host processes. Within host cells, their developmental cycle takes place inside non-acidified vacuoles termed inclusions. An inclusion membrane composed primarily of secreted chlamydial synthesized proteins called Incs encloses the inclusion. At this location, Incs have...
    Resource Type:
    Dissertation
    Full Text:
    , Dr. Luiz Bermudez, Dr. Mahfuz Sarker, Dr. Karen Guillemin, and Dr. Barbara Taylor who all have an