This thesis details my investigation of some pharmaceuticals and natural products on the transport of drugs which are substrates of P-glycoprotein (P-gp), such as cyclosporin A (CSA) and digoxin by using Caco-2 and MDCKII-MDR1 drug transport models. Three objectives were performed to address this goal. The first objective was to...
This dissertation presents a dual-path 2-0 MASH (Multi-stAge-noise -SHaping) ADC with two verified digital corrections of DAC mismatch error and quantization noise leakage. By using these two techniques, the requirements for the analog circuits are greatly relaxed. The dual-path structure generates two outputs, one only composed of conversion errors, the...
The demand for portable electronic systems and the continued
down-scaling of device dimensions resulted in rapid improvement in
the performance of integrated systems. Several low-voltage design
techniques have been proposed to operate analog circuits with sub-1V
supply. However, these techniques require higher power consumption
to achieve large dynamic range while...