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Filtering by: Creator Helfand, Stuart C. File Format pdf License Attribution-NonCommercial-NoDerivs 3.0 United States

Effect of Protease Inhibitors on Steady-State Pharmacokinetics of Oral Norethindrone Contraception in HIV-Infected Women

Creator:

Atrio, Jessica, Stanczyk, Frank Z., Neely, Michael, Cherala, Ganesh, Kovacs, Andrea, and Mishell, Daniel R., Jr.

Abstract:

OBJECTIVE: Pharmacokinetic interactions exist between combined oral contraceptives and protease inhibitors (PI). However, such information is lacking for progestin-only oral contraception. We sought to define the steady-state pharmacokinetic interaction between norethindrone (NET) and PI in HIV-infected women. METHODS AND DESIGN: We conducted an open-label, prospective, nonrandomized trial to characterize the...

Resource Type:

Article

Full Text:

stored at 220°C until analyzed. Treatment For the treatment, 0.35-mg NET (Jolivette) was ordered