OBJECTIVE: Pharmacokinetic interactions exist between combined
oral contraceptives and protease inhibitors (PI). However, such
information is lacking for progestin-only oral contraception. We
sought to define the steady-state pharmacokinetic interaction between
norethindrone (NET) and PI in HIV-infected women.
METHODS AND DESIGN: We conducted an open-label, prospective,
nonrandomized trial to characterize the...
We measure the forward-backward asymmetries A[subscript]FB of charged Ξ and Ω baryons produced in p (p) over bar collisions recorded by the D0 detector at the Fermilab Tevatron collider at √s = 1.96 TeV as a function of the baryon rapidity y. We find that the asymmetries A[subscript]FB for charged...
Resilient interdependent critical infrastructures (CIs) can better withstand cascading failures in disruptive events. This study proposes network expansion as a resilience improvement strategy for interdependent CIs and evaluates the influence of topology in interdependent network design for resilience optimization under disruption uncertainty. A resilience score consisting of network complexity and...
Abstract: Background: Chronic exposure to arsenic in drinking water is associated with increased risk of type 2 diabetes mellitus (T2DM) but the underlying molecular mechanism remains unclear.
Objectives: This study evaluated the interaction between single nucleotide polymorphisms (SNPs) in genes associated with diabetes and arsenic exposure in drinking water on...
This study explores how a platform enables social media influencers to promulgate a consumption ideology. We show how gun influencers, or “gunfluencers,” use Instagram to link products, activities, and meanings to Second Amendment ideology—a gun-centric belief system in the United States colloquially known as “2A ideology.” Through a qualitative study...
Although Mexico is one of the major lime producing countries in the world the crop is not completely utilized. In this paper some ideas are reviewed in relation to various possible products that can be obtained from the efficient processing of limes. Among these are the extraction of the juice,...
Research relying on remotely sensed data on land use and deforestation has exploded in recent years. While satellite-based measures have clear advantages in terms of coverage, the presence of measurement error within these products is often overlooked. Here, we detail the econometric implications of these errors when analyzing the determinants...
The Goose Lake Basin, situated on the border of Oregon and California, USA, faces significant challenges from drought, wildfire, and other environmental stressors. This region hosts numerous endemic fish species such as the Goose Lake redband trout (Oncorhynchus mykiss newberri), Goose Lake lamprey (Entosphenus sp.), Goose Lake tui chub (Siphateles...
Throughout their lifetime individuals are exposed to complex mixtures of chemicals. The study of chemical mixtures is an internationally recognized research priority, but seemingly complex challenge. To reduce the intricacy of studying mixtures, researchers have identified different prioritization methods based on exposure or the toxicity of chemicals. However, understanding the...