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Filtering by: Has journal Veterinary Clinics of North America-Small Animal Practice Has journal sim International Journal of Nanomedicine

Phthalocyanine-loaded graphene nanoplatform for imaging-guided combinatorial phototherapy

Creator:

Taratula, Olena, Patel, Mehulkumar, Schumann, Canan, Naleway, Michael A., Pang, Addison J., He, Huixin, and Taratula, Oleh

Abstract:

We report a novel cancer-targeted nanomedicine platform for imaging and prospect for future treatment of unresected ovarian cancer tumors by intraoperative multimodal phototherapy. To develop the required theranostic system, novel low-oxygen graphene nanosheets were chemically modified with polypropylenimine dendrimers loaded with phthalocyanine (Pc) as a photosensitizer. Such a molecular design...

Resource Type:

Article

Full Text:

nm excitation/ emission filters. In vivo imaging An animal (nude mice) model of human ovarian