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Targeting an Essential GTPase Obg for the Development of Broad-Spectrum Antibiotics

Creator:: Bonventre, Josephine A., Zielke, Ryszard A., Korotkov, Konstantin V., and Sikora, Aleksandra E.
Abstract:: A promising new drug target for the development of novel broad-spectrum antibiotics is the highly conserved small GTPase Obg (YhbZ, CgtA), a protein essential for the survival of all bacteria including Neisseria gonorrhoeae (GC). GC is the agent of gonorrhea, a prevalent sexually transmitted disease resulting in serious consequences on...
Resource Type:: Article
Full Text:: -Spectrum Antibiotics Josephine A. Bonventre1, Ryszard A. Zielke1, Konstantin V. Korotkov2, Aleksandra E

Modelling Associations between Public Understanding, Engagement and Forest Conditions in the Inland Northwest, USA

Creator:: Hartter, Joel, Stevens, Forrest R., Hamilton, Lawrence C., Congalton, Russell G., Ducey, Mark J., and Oester, Paul T.
Abstract:: Opinions about public lands and the actions of private non-industrial forest owners in the western United States play important roles in forested landscape management as both public and private forests face increasing risks from large wildfires, pests and disease. This work presents the responses from two surveys, a random-sample telephone...
Resource Type:: Article

Risk of Exposure to Eastern Equine Encephalomyelitis Virus Increases with the Density of Northern Cardinals

Creator:: Estep, Laura K., McClure, Christopher J. W., Vander Kelen, Patrick, Burkett-Cadena, Nathan D., Sickerman, Stephen, Hernandez, José, Jinright, Joseph, Hunt, Brenda, Lusk, John, Hoover, Victor, Armstrong, Keith, Stark, Lillian M., Hill, Geoffrey E., and Unnasch, Thomas R.
Abstract:: For a variety of infectious diseases, the richness of the community of potential host species has emerged as an important factor in pathogen transmission, whereby a higher richness of host species is associated with a lowered disease risk. The proposed mechanism driving this pattern is an increased likelihood in species-rich...
Resource Type:: Article
Full Text:: , Tampa, Florida, United States of America, 4 South Walton County Mosquito Control District, Santa Rosa

Viruses in unexplained encephalitis cases in American black bears (Ursus americanus)

Creator:: Alex, Charles E., Fahsbender, Elizabeth, Altan, Eda, Bildfell, Robert, Wolff, Peregrine, Jin, Ling, Black, Wendy, Jackson, Kenneth, Woods, Leslie, Munk, Brandon, Tse, Tiffany, Delwart, Eric, and Pesavento, Patricia A.
Abstract:: Viral infections were investigated in American black bears (Ursus americanus) from Nevada and northern California with and without idiopathic encephalitis. Metagenomics analyses of tissue pools revealed novel viruses in the genera Circoviridae, Parvoviridae, Anelloviridae, Polyomaviridae, and Papillomaviridae. The circovirus and parvovirus were of particular interest due to their potential importance...
Resource Type:: Article
Full Text:: cause or contributor to disease in American black bears. Introduction American black bears (Ursus

Distillation Time as Tool for Improved Antimalarial Activity and Differential Oil Composition of Cumin Seed Oil

Creator:: Zheljazkov, Valtcho D., Gawde, Archana, Cantrell, Charles L., Astatkie, Tess, and Schlegel, Vicki
Abstract:: A steam distillation extraction kinetics experiment was conducted to estimate essential oil yield, composition, antimalarial, and antioxidant capacity of cumin (Cuminum cyminum L.) seed (fruits). Furthermore, regression models were developed to predict essential oil yield and composition for a given duration of the steam distillation time (DT). Ten DT durations...
Resource Type:: Article
Full Text:: University, 48037 County 788 Road, Adams, Oregon 97810, United States of America, 2 Natural Products

Spatial and Temporal Variability of Macroinvertebrates in Spawning and Non-Spawning Habitats during a Salmon Run in Southeast Alaska

Creator:: Campbell, Emily Y., Merritt, Richard W., Cummins, Kenneth W., and Benbow, M. Eric
Abstract:: Spawning salmon create patches of disturbance through redd digging which can reduce macroinvertebrate abundance and biomass in spawning habitat. We asked whether displaced invertebrates use non-spawning habitats as refugia in streams. Our study explored how the spatial and temporal distribution of macroinvertebrates changed during a pink salmon (Oncorhynchus gorbuscha) spawning...
Resource Type:: Article
Full Text:: phenology, or other variables. We propose that certain in-stream habitats could be important for the

Development and Infectious Disease in Hosts with Complex Life Cycles

Creator:: Searle, Catherine L., Xie, Gisselle Yang, and Blaustein, Andrew R.
Abstract:: Metamorphosis is often characterized by profound changes in morphology and physiology that can affect the dynamics of species interactions. For example, the interaction between a pathogen and its host may differ depending on the life stage of the host or pathogen. One pathogen that infects hosts with complex life cycles...
Resource Type:: Article
Full Text:: may differ depending on the life stage of the host or pathogen. One pathogen that infects hosts with

Evaluating the Return in Ecosystem Services from Investment in Public Land Acquisitions

Creator:: Kovacs, Kent, Polasky, Stephen, Nelson, Erik, Keeler, Bonnie L., Pennington, Derric, Plantinga, Andrew J., and Taff, Steven J.
Abstract:: We evaluate the return on investment (ROI) from public land conservation in the state of Minnesota, USA. We use a spatially-explicit modeling tool, the Integrated Valuation of Ecosystem Services and Tradeoffs (InVEST), to estimate how changes in land use and land cover (LULC), including public land acquisitions for conservation, influence...
Resource Type:: Article
Full Text:: the original author and source are credited. Funding: The authors have no support or funding to

Invasive Congeners Differ in Successional Impacts across Space and Time

Creator:: David, Aaron S., Zarnetske, Phoebe L., Hacker, Sally D., Ruggiero, Peter, Biel, Reuben G., and Seabloom, Eric W.
Abstract:: Invasive species can alter the succession of ecological communities because they are often adapted to the disturbed conditions that initiate succession. The extent to which this occurs may depend on how widely they are distributed across environmental gradients and how long they persist over the course of succession. We focus...
Resource Type:: Article
Full Text:: by A. breviligulata, forest, or developed land over a 23-yr period. Ammophila breviligulata likely in

Development of Partial Ontogenic Resistance to Powdery Mildew in Hop Cones and Its Management Implications

Creator:: Twomey, Megan C., Wolfenbarger, Sierra N., Woods, Joanna L., and Gent, David H.
Abstract:: Knowledge of processes leading to crop damage is central to devising rational approaches to disease management. Multiple experiments established that infection of hop cones by Podosphaera macularis was most severe if inoculation occurred within 15 to 21 days after bloom. This period of infection was associated with the most pronounced...
Resource Type:: Article
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ScholarsArchive@OSU

Targeting an Essential GTPase Obg for the Development of Broad-Spectrum Antibiotics

Modelling Associations between Public Understanding, Engagement and Forest Conditions in the Inland Northwest, USA

Risk of Exposure to Eastern Equine Encephalomyelitis Virus Increases with the Density of Northern Cardinals

Viruses in unexplained encephalitis cases in American black bears (Ursus americanus)

Distillation Time as Tool for Improved Antimalarial Activity and Differential Oil Composition of Cumin Seed Oil

Spatial and Temporal Variability of Macroinvertebrates in Spawning and Non-Spawning Habitats during a Salmon Run in Southeast Alaska

Development and Infectious Disease in Hosts with Complex Life Cycles

Evaluating the Return in Ecosystem Services from Investment in Public Land Acquisitions

Invasive Congeners Differ in Successional Impacts across Space and Time

Development of Partial Ontogenic Resistance to Powdery Mildew in Hop Cones and Its Management Implications

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