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  • Collagen Network and the Mechanical Microenvironment of Cancer Cells

    Creator:
    Sun, Bo
    Abstract:
    中文摘要：本文以第一类胶原纤维网络为例，着重分析了癌细胞三维微环境的多尺度结构及力学特征。对应于细胞与细胞外介质结合的蛋白集团，单个细胞，以及细胞群体，分别由单个纤维（或亚纤维），纤维集束，以及纤维网络整体来决定相应的力学环境。我们同时也讨论了胶原纤维（及其类似材料）的局限性。
    Resource Type:
    Article
    Full Text:
    . Balkwill, F., Capasso, M. & Hagemann, T., 2012. The tumor microenvironment at a glance. Journal of Cell