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Filtering by: Language English [eng] Remove constraint Language: English [eng] Non-Academic Affiliation Linus Pauling Institute Remove constraint Non-Academic Affiliation: Linus Pauling Institute Resource Type Dissertation Remove constraint Resource Type: Dissertation

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Brassicas, microbes, and metabolites : a multi-omic investigation of cruciferous vegetable phytochemical metabolism

Creator:

Bouranis, John A.

Abstract:

Phytochemicals from cruciferous vegetables, such as broccoli, contain a multitude of bioactive compounds that prevent and suppress cancer and promote optimal health. Some of the health promoting effects of cruciferous vegetables are attributed to a class of compounds known as isothiocyanates (ITCs), a potent nuclear factor erythroid 2–related factor 2...

Resource Type:

Dissertation
The Role of Cellular Senescence in the Development of Alzheimer's Disease

Creator:

Riordan, Ruben

Abstract:

Alzheimer’s Disease (AD) is a neurodegenerative pathology currently affecting nearly 44 million individuals worldwide, yet there are not currently any effective treatments or preventions for AD despite the rapid development in our understanding of the disease over the last four decades. The medical and sanitary innovations of the last century...

Resource Type:

Dissertation
Characterization of the Mechanisms of Action and Molecular Targets of Hop-derived Flavonoids in the Mitigation of Obesity-related Metabolic Impairments

Creator:

Paraiso, Ines L.

Abstract:

Obesity is a complex multifactorial disease resulting from excessive energy intake compared to energy expenditure. The excess energy is mostly stored as fat in enlarged adipocytes, but some lipids may infiltrate other organs such as the liver to form ectopic fat. Adipose tissue and ectopic fat produce and secrete a...

Resource Type:

Dissertation
Investigation of Procyanidins Used in Botanical Dietary Supplements

Creator:

Rue, Emily A.

Abstract:

Polyphenolic compounds found in foods such as fruits, vegetables, legumes, nuts and grains, are an integral part of the human diet. Within polyphenols, proanthocyanidins are referred to as condensed tannins and encompass procyanidins, propelargonidins and prodelphinidins. Among these, procyanidins are the largest group. Recent interest in these compounds is related...

Resource Type:

Dissertation

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Academic Affiliation

College of Pharmacy2
Biochemistry and Biophysics1
Biological and Population Health Sciences1

Advisor

Ho, Emily1
Perez, Viviana I.1
Stevens, Jan F.1
van Breemen, Richard B.1

Commencement Year

Commencement Year range begin – Commencement Year range end

Current results range from 2021 to 2023

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Committee Member

Franco, Maria C.1
Gable, Kevin1
Hord, Norman G.1
Hsu, Victor L.1
Ishmael, Jane1
more Committee Members »

Creator

Bouranis, John A.1
Paraiso, Ines L.1
Riordan, Ruben1
Rue, Emily A.1

Date

Date range begin – Date range end

Current results range from 2021 to 2023

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Decade

2020-20294

Degree Field

Pharmaceutical Sciences2
Biochemistry and Biophysics1
Nutrition1

Degree Level

Doctoral4

Degree Name

Doctor of Philosophy (Ph.D.)4

Language

English [eng][remove]4

License

All rights reserved4

Non-Academic Affiliation

Linus Pauling Institute[remove]4

Peer Reviewed

No3
Yes1

Resource Type

Dissertation[remove]4

Rights Statement

In Copyright4

Subject

Aging1
Alzheimer's disease1

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