Index Catalog // ScholarsArchive@OSU

Protein Adducts of Aldehydic Lipid Peroxidation Products: Identification and Characterization of Protein Adducts Using an Aldehyde/Keto Reactive Probe in Combination with Mass Spectrometry

Creator:: Maier, Claudia S., Chavez, Juan, Wang, Jing, and Wu, Jianyong
Abstract:: This chapter describes a mass spectrometry-based strategy that facilitates the unambiguous identification and characterization of proteins modified by lipid peroxidation-derived 2-alkenals. The approach employs a biotinylated hydroxyl amine derivative as an aldehyde/keto reactive probe in conjunction with selective enrichment and tandem mass spectrometric analysis. Methodological details are given for model...
Resource Type:: Part of Book
Full Text:: REACTIVE PROBE IN COMBINATION WITH MASS SPECTROMETRY By CLAUDIA S. MAIER, JUAN CHAVEZ, JING WANG

Nonmuscle myosins II-B and Va are components of detergentresistant membrane skeletons derived from mouse forebrain

Creator:: Ishmael, Jane E., Safic, Masa, Amparan, David, Vogel, Walter K., Pham, Tuyen, Marley, Kevin, Filtz, Theresa M., and Maier, Claudia S.
Abstract:: Myosins are actin-based molecular motors that may have specialized trafficking and contractile functions in cytoskeletal compartments that lack microtubules. The postsynaptic excitatory synapse is one such specialization, yet little is known about the spatial organization of myosin motor proteins in the mature brain. We used a proteomics approach to determine...
Resource Type:: Preprint and Article
Full Text:: -5783 Fax: (541) 737-3999 Email: jane.ishmael@oregonstate.edu and Claudia S. Maier, Ph.D

A Multiplex Biomarker Approach for the Diagnosis of Transitional Cell Carcinoma from Canine Urine

Creator:: Bracha, Shay, McNamara, Michael, Hilgart, Ian, Milovancev, Milan, Medlock, Jan, Goodall, Cheri, Wickramasekara, Samanthi, and Maier, Claudia S.
Abstract:: Transitional cell carcinoma (TCC), the most common cancer of the urinary bladder in dogs, is usually diagnosed at an advanced disease stage with limited response to chemotherapy. Commercial screening tests lack specificity and current diagnostic procedures are invasive. A proof of concept pilot project for analyzing the canine urinary proteome...
Resource Type:: Article

A freshwater cyanophage whose genome indicates close relationships to photosynthetic marine cyanomyophages

Creator:: Dreher, Theo W., Brown, Nathan, Bozarth, Connie S., Schwartz, Andrew D., Riscoe, Erin, Thrash, Cameron, Bennett, Samuel E., Tzeng, Shin-Cheng, and Maier, Claudia S.
Abstract:: Bacteriophage S-CRM01 has been isolated from a freshwater strain of Synechococcus and shown to be present in the upper Klamath River valley in northern California and Oregon. The genome of this lytic T4-like phage has a 178,563 bp circular genetic map with 297 predicted protein-coding genes and 33 tRNA genes...
Resource Type:: Article

Highly Regioselective Nitrile Oxide Dipolar Cycloadditions with ortho-Nitrophenyl Alkynes

Creator:: McIntosh, Melissa L., Naffziger, Michael R., Ashburn, Bradley O., Zakharov, Lev N., and Carter, Rich G.
Abstract:: The dipolar cylcoadditions of ortho-nitrophenyl alkynes with aryl nitrile oxides has been demonstrated. A range of substituents are tolerated on the alkyne. These reactions proceed with excellent levels of regioselectivity. Subsequent functionalization of the isoxazole scaffold has been demonstrated.
Resource Type:: Article
Full Text:: Claudia Maier and Dr. Jeff Morré (OSU) for mass spectra data. Finally, we are grateful to 90 10

Mass spectrometric analysis of proteins and peptides : elucidation of the folding pathways of recombinant human macrophage colony stimulating factor beta

Creator:: Zhang, Yuan Heidi
Abstract:: Recombinant human macrophage colony stimulating factor beta (rhm-CSFβ) is a glycoprotein that stimulates the proliferation, differentiation and survival of cells belonging to the monocyte-macrophage lineage. It contains nine inter-subunit and intra-subunit disulfide bonds and represents an excellent model system for studying disulfide bond formation during protein folding because the assembly...
Resource Type:: Dissertation
Full Text:: thank Dr. Claudia Maier and Dr. XuGuang Yan for the discussions regarding rhm-CSFO and hydrogen

Hemoglobin adducts of the organophosphate insecticide azinphos-methyl

Creator:: Bailey, Bonnie J.
Abstract:: Reported here is an investigation to determine if azinphos-methyl (AZM), an organophosphate insecticide, adducts to hemoglobin, and if so, whether the hemoglobin adduct could be used as a quantitative marker of occupational AZM exposure. We hypothesized that AZM, or a metabolite of AZM, binds to hemoglobin in erythrocytes forming an...
Resource Type:: Dissertation
Full Text:: . I thank Don Griffin and Claudia Maier for assistance with mass spectrometry. I thank Pat Thomson

Planning officials in Oregon : directory [1975]

Creator:: Pease, James R. (James Robert), Beller, Luanne, and Oregon State University. Extension Service
Abstract:: Published July 1975. Facts and recommendations in this publication may no longer be valid. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu/catalog
Resource Type:: Technical Report
Full Text:: Rambery Hal Lutz Granville Stuart Claudia Marthaller Rt. 1 Box 262 Toledo, OR 97391 Planning Director

Mass spectrometric studies on peptides and proteins : conformations of Escherichia coli Thioredoxin and its alkylated adducts studied by hydrogen/deuterium exchange and HPLC-electrospray ionization mass spectrometry

Creator:: Kim, Moo-young
Abstract:: E. coli thioredoxin (TRX) was modified by the episulfonium ion derived from S-(2-chloroethyl)glutathione (CEG) or S-(2-chloroethyl)cysteine (CEC). The alkylation site was located at Cys-32, which was confirmed by tandem mass spectrometry. Two forms of native TRX, Oxi- and Red-TRX, and two modified TRXs, GS- and Cys-TRX, were examined by hydrogen/deuterium...
Resource Type:: Dissertation
Full Text:: studies on proteins. I thank Dr. Claudia Maier and Dr. Xuguang Yan for their enthusiasm, advice, and

Acute phase proteins in rainbow trout (Oncorhynchus mykiss)

Creator:: Gerwick, Lena
Abstract:: The acute phase response (APR) includes an early response of the innate immune system to an inflammatory agent. Acute phase proteins (APP) are produced at increased rates in the liver during this response. The APR has been well characterized in mammals, but it is unclear to what degree teleosts mount...
Resource Type:: Dissertation

ScholarsArchive@OSU

Protein Adducts of Aldehydic Lipid Peroxidation Products: Identification and Characterization of Protein Adducts Using an Aldehyde/Keto Reactive Probe in Combination with Mass Spectrometry

Nonmuscle myosins II-B and Va are components of detergentresistant membrane skeletons derived from mouse forebrain

A Multiplex Biomarker Approach for the Diagnosis of Transitional Cell Carcinoma from Canine Urine

A freshwater cyanophage whose genome indicates close relationships to photosynthetic marine cyanomyophages

Highly Regioselective Nitrile Oxide Dipolar Cycloadditions with ortho-Nitrophenyl Alkynes

Mass spectrometric analysis of proteins and peptides : elucidation of the folding pathways of recombinant human macrophage colony stimulating factor beta

Hemoglobin adducts of the organophosphate insecticide azinphos-methyl

Planning officials in Oregon : directory [1975]

Mass spectrometric studies on peptides and proteins : conformations of Escherichia coli Thioredoxin and its alkylated adducts studied by hydrogen/deuterium exchange and HPLC-electrospray ionization mass spectrometry

Acute phase proteins in rainbow trout (Oncorhynchus mykiss)

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