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Filtering by: Creator Chalasani, Naga Language English [eng]

Genetic Polymorphism of Cytochrome P450 4F2, Vitamin E Level and Histological Response in Adults and Children with Nonalcoholic Fatty Liver Disease Who Participated in PIVENS and TONIC Clinical Trials

Creator:

Athinarayanan, Shaminie, Wei, Rongrong, Zhang, Min, Bai, Shaochun, Traber, Maret G., Yates, Katherine, Cummings, Oscar W., Molleston, Jean, Liu, Wanqing, and Chalasani, Naga

Abstract:

Vitamin E improved liver histology in children and adults with NAFLD who participated in TONIC and PIVENS clinical trials, but with significant inter-individual variability in its efficacy. Cytochrome P450 4F2 (CYP4F2) is the major enzyme metabolizing Vit E, with two common genetic variants (V433M, rs2108622 and W12G, rs3093105) found to...

Resource Type:

Article
Spatiotemporal Distributions of Bacteria in the Cheddar Production Environment

Creator:

Johnson, Jared D.

Abstract:

Given the many significant roles that bacteria play in modern food manufacturing, it is crucial that we have a fundamental understanding of how bacterial communities assemble and behave in the food manufacturing environment. The focus of this dissertation was to investigate both the spatial and temporal distributions of microbial communities...

Resource Type:

Dissertation