Contextualization is a curricular approach and a learning process in which science content knowledge is intentionally situated within a context where that knowledge can be authentically applied or observed. Many recent science education reforms include contextualization as a central tenet. Our goal in this review was to examine commonalities across...
Vaccinia virus-infected animal cells have been used to
study the interactions between the replication of
deoxyribonucleic acid (DNA) and the biosynthesis of its
nucleotide precursors. Some antimetabolites that inhibit
DNA replication have as their targets enzymes of nucleotide
biosynthesis. Furthermore, the disruption of nucleotide
metabolism can alter the fidelity of...
Imbalanced deoxyribonucleoside triphosphate (dNTP) pools are mutagenic for DNA synthesis in both intact cells and cell-free replication systems. Almost certainly, such mutagenesis involves competition between correctly and incorrectly base-paired precursors at replication sites. However, there are certain differences between the intact cell and cell-free systems that do not always allow...
To predict future coastal hazards, it is important to quantify any links between climate drivers and spatial patterns of coastal change. However, most studies of future coastal vulnerability do not account for the dynamic components of coastal water levels during storms, notably wave-driven processes, storm surges and seasonal water level...
A synthesis of over 2000 paleoclimate proxy records is performed via a data assimilation framework that expands upon previous efforts by implementing a suite of physically-based proxy system models, and which provides the first example of an observationally independent, multi-seasonal (DJFM, JJAS) paleoclimate reanalysis. This methodology is contrasted against previous...
Internal variability in twenty-first-century summer Arctic sea ice loss and its relationship to the large-scale atmospheric circulation is investigated in a 39-member Community Climate System Model, version 3 (CCSM3) ensemble for the period 2000–61. Each member is subject to an identical greenhouse gas emissions scenario and differs only in the...
We use the NCEP/NCAR Reanalysis (NCEP)
and the MPI/ECHAM5 general circulation model to drive
the RegCM3 regional climate model to assess the ability of
the models to reproduce the spatiotemporal aspects of the
Pacific-North American teleconnection (PNA) pattern.
Composite anomalies of the NCEP-driven RegCM3 simulations
for 1982–2000 indicate that the...
Methane fluxes into the oceans are largely dependent on the methane phase as it migrates upward through the sediments. Here we document decoupled methane transport by gaseous and aqueous phases in Storfjordrenna (offshore Svalbard) and propose a three-stage evolution model for active seepage in the region where gas hydrates are...
The state of the California Current system (CCS) since spring 2010 has evolved in response to the development of cooler La Nina following the dissipation of the relatively weak and short-lived El Nino event of 2009-2010. The 2009-2010 El Nino appears to have dissipated quite rapidly in early spring 2010,...
A disproportionate amount of HIV/AIDS cases each year occur among African Americans. The purpose of this study was to review the numerous studies on HIV/AIDS conspiracy beliefs and their effects into one document. This research was done using research databases to indentify peer-reviewed journal articles on HIV/AIDS conspiracy beliefs, and...