Background: Main objectives were to determine to what extent Smartamine M (SM) supplementation to a prepartal higher-energy diet could alter neutrophil (PMN) and liver tissue immunometabolic biomarkers, and whether those responses were comparable to those in cows fed a prepartal lower-energy diet (CON).
Results: Twenty-eight multiparous Holstein cows were fed...
The hypothesis of the study was that inhibition of PPAR/ increases glucose uptake and lactose synthesis in bovine mammary epithelial cells by reducing the expression of the glucose transporter mRNA destabiliser calreticulin. Three experiments were conducted to test the hypothesis using immortalised bovine mammary alveolar (MACT) and primary bovine mammary...
During the peripartum period (3 weeks before through 3 weeks after calving, a.k.a. “transition”), high producing dairy cows experience, among others, , oxidative stress and immune suppression that compromise performance and increased incidence of diseases.Among trace minerals, supplementation of Selenium (Se) can help to improve the transition by enhancing glutathione...
Oxidative dysfunction can affect dairy animals during periods of heightened stress, particularly during the transition from pregnancy to lactation and during diseases, such as intramammary infection (IMI), and can contribute to increased inflammation, immune dysfunction, and cell death. As such, methods for ameliorating oxidative stress and restoring redox regulation may...
Nutrigenomics is a branch of nutrition that seeks to elucidate the relationship between dietary components and expression of genes. Certain bioactive compounds present in the diet have the potential to modulate transcription of genes through their interactions with ligand-dependent nuclear receptors, a series of transcriptional regulators capable of sensing intracellular...
The overall objective of this dissertation study was to develop and validate the performance of cellulose nanomaterials (CNs) incorporated fruit coatings for improving the storability of postharvest pears and bananas under various storage conditions. Four specific studies were conducted to fulfill the research objectives as stated below.
First, cellulose nanocrystal...
Besides enabling an enhanced mobile broadband access, fifth-generation (5G) wireless mobile networks are envisioned to support the connectivity of massive, heterogeneous Internet of Things (IoT) devices. Connecting these devices through 5G systems and providing them with their needed data rates require huge amounts of spectrum and power resources, thus calling...
Today nano scale materials are being used for wide range of applications. One promising topic in nano scale materials is using them for reinforcement of different polymeric materials to reach desirable stiffness properties. The stiffness of these materials is mostly found experimentally because the nanocomposite community lacks a decent analytical...
Mastitis is a major endemic disease in dairy cows resulting in significant economic losses for the dairy industry. The peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor that is able to bind and be activated by natural (e.g., fatty acids) and synthetic (e.g. thiazolidinedione) compounds. PPARγ plays important roles...
It is desirable for complex engineered systems to perform missions efficiently and economically, even when these missions' complex, variable, long-term operational profiles make it likely for hazards to arise. It is thus important to design these systems to be resilient so that they will actively prevent and recover from hazards...