Index Catalog // ScholarsArchive@OSU

Optimizing Methods to Assess Nanoparticle Biodistribution in Embryonic Zebrafish

Creator:: Pfarr, Shaylin H.
Abstract:: As nanoparticle (NP) research and development expands, the significance of NP biodistribution effects on toxicity increases. A reliable method for measuring NP biodistribution is critical. Hyperspectral Imaging (HSI) is capable of accurately quantitating NP biodistribution within embryonic zebrafish with incredibly high precision. Before HSI processing, the embryo must be sectioned...
Resource Type:: Honors College Thesis
Full Text:: Engineering _____________________________________________________________________ Bryan Harper

Developmental effects of micro- and nanoscale tire particles and recycled rubber on zebrafish

Creator:: Mottern, Taylor H.
Abstract:: Plastics have become an essential part of everyone lives, found in almost every product made today. Tires only make up a fraction of these products but as their use increasing so does the microplastics that flake off. Many studies have evaluated the toxic effects of tire particles on aquatic environments...
Resource Type:: Honors College Thesis
Full Text:: Harper, Mentor, representing Chemical, Biological, and Environmental Engineering Bryan Harper

Environmental Transformations of Nanoparticles in Natural Water Systems using a Hydrophobic and Hydrophilic Dye Assay

Creator:: Turnquist, Macklin C.
Abstract:: Nanoparticles (NPs) are generally defined as particles <100 nanometers (nm) in size in one dimension. Despite increasing industrial usage of TiO2 NPs in sunscreens, cosmetics, and water remediation little is known of their environmental behavior. The primary goal of this research was to develop a rapid method for determining the...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Bryan Harper, Committee Member, representing Department of Environmental and Molecular

"Instead of tumbleweed, we have mitigation systems" : an ethnography of toxics risk, mitigation, and advocacy in IBM's deindustrialized birthplace

Creator:: Little, Peter C.
Abstract:: This dissertation draws on ethnographic data and political ecological theory to analyze the experience of residents living in the IBM-Endicott Superfund site in Endicott, New York. Combining in-depth narratives and quantitative measures from a household survey, it highlights residents' perceptions of 1) environmental health risk, 2) risk mitigation, 3) deindustrialization...
Resource Type:: Dissertation
Full Text:: Bryan Tilt This dissertation draws on ethnographic data and political ecological theory to

Assessing Changes in Biological Interactions of Lipid-Coated Gold and Silver Nanoparticles Based on Physicochemical Properties

Creator:: Engstrom, Arek Mackenzie
Abstract:: Nanoparticles (NPs), particles defined by their size in a single dimension (1-100 nm), are being increasingly incorporated into commercial and industrial products due to their high surface area to volume ratio that gives them unique properties, such as optical tunability and higher reactivity than their bulk counterparts. NPs can be...
Resource Type:: Masters Thesis
Full Text:: am today. I would also like to thank Bryan Harper, who provided support to me as a mentor, in

An in silico Approach to Determine the Influence of Surface Chemical Properties on the Toxicity of Engineered Zinc Oxide Nanoparticles

Creator:: Zhou, Zitao
Abstract:: Nanotechnology products have long since made their way to markets around the world increasing the concerns about whether nanomaterials pose a risk to our environment or health. It has been suggested that engineered nanomaterial (ENM) with broad applications and rapid commercialization need better risk assessment and regulation. However, the refinement...
Resource Type:: Masters Thesis
Full Text:: . Stacey Harper for her continuous encouragement and wise advice. Thanks to Bryan Harper’s great

Addressing the Risks of Nanoscale Polymers: Exposure, Behavior, and Toxicity

Creator:: Stine, Jared
Abstract:: Nanoscale polymers (including nanoplastics) are widely present through commerce and make their way into the environment. As the improper disposal of plastic waste leads to continued accumulation and degradation of plastic pollution, the presence of plastic particles less than 1 micron (μm) in size (nanoplastics) will increase. Heightened concern over...
Resource Type:: Dissertation
Full Text:: advisor Dr. Stacey Harper and Bryan Harper for being fantastic mentors, teachers, and guides during my

A Nano-sized Dose of Toxicology: Elucidating the Disconnect Between Nanomaterial Dosimetry and Biological Effects

Creator:: Slattery, Matthew R.
Abstract:: Nanotechnologies continue to permeate a multitude of industries, with diverse applications ranging from pesticides to fuel additives. The unusual behavior of nanomaterials that drives their innovation also complicates the job of toxicologists tasked with assessing their potential environmental and public health impacts. This dissertation investigates the underlying reasons for uncertainty...
Resource Type:: Dissertation
Full Text:: the dream alive. Bryan Harper, for never failing to produce a smile while preaching the cyclical

Novel Approaches to Evaluate the Environmental Impacts of Nanomaterials

Creator:: Wu, Fan
Abstract:: Numerous studies have shown that some nanomaterials are highly toxic to aquatic organisms and can potentially disrupt overall community health; however, current methods to evaluate the nanomaterials environmental impacts rarely consider the environmental realism or provide sufficient detail on the impact at the community level. Here we demonstrate three approaches...
Resource Type:: Dissertation
Full Text:: development as a scientist and researcher. I also would like to thank Bryan Harper especially, his

Assessing the Impacts of Size, Structure, and Surface Chemistry on the Toxicity of Two High Production Organic Nanomaterials using the Embryonic Zebrafish Model

Creator:: Meredith, Ailcea N.
Abstract:: The low risk and sustainable implementation of nanotechnology requires understanding how nanomaterial physicochemical properties influence their toxicity. Major drivers of toxicity need to be avoided while maximizing product efficacy so nanomaterials can be produced to best serve their applications and be of low risk when intentionally or unintentionally released into...
Resource Type:: Masters Thesis
Full Text:: . Meredith with advice from Stacey Harper and Bryan Harper. All experiments and statistical analysis were

ScholarsArchive@OSU

Optimizing Methods to Assess Nanoparticle Biodistribution in Embryonic Zebrafish

Developmental effects of micro- and nanoscale tire particles and recycled rubber on zebrafish

Environmental Transformations of Nanoparticles in Natural Water Systems using a Hydrophobic and Hydrophilic Dye Assay

"Instead of tumbleweed, we have mitigation systems" : an ethnography of toxics risk, mitigation, and advocacy in IBM's deindustrialized birthplace

Assessing Changes in Biological Interactions of Lipid-Coated Gold and Silver Nanoparticles Based on Physicochemical Properties

An in silico Approach to Determine the Influence of Surface Chemical Properties on the Toxicity of Engineered Zinc Oxide Nanoparticles

Addressing the Risks of Nanoscale Polymers: Exposure, Behavior, and Toxicity

A Nano-sized Dose of Toxicology: Elucidating the Disconnect Between Nanomaterial Dosimetry and Biological Effects

Novel Approaches to Evaluate the Environmental Impacts of Nanomaterials

Assessing the Impacts of Size, Structure, and Surface Chemistry on the Toxicity of Two High Production Organic Nanomaterials using the Embryonic Zebrafish Model

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