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Evolutionary Genomic Responses to Mitochondrial Dysfunction in Caenorhabditis elegans

Creator:

Wernick, Riana I.

Abstract:

Understanding the impact of mitochondrial dysfunction on genome evolution has the potential not only to provide new insights on the basic evolutionary processes influencing mitochondrial and nuclear genomes, but may also reveal novel avenues for evolutionary adaptive recovery from harmful mutations. Aberrant mitochondrial activity is fundamental to the pathology of...

Resource Type:

Dissertation