Understanding the mechanisms that regulate local species diversity and community structure is a perennial goal of ecology. Local community structure can be viewed as the result of numerous local and regional processes; these processes act as filters that reduce the regional species pool down to the observed local community. In...
Local aquatic insect diversity and community structure is the result of multiple local and regional factors, and observed patterns depend upon the spatial and temporal scale under examination. Isolated stream systems in arid regions represent a new challenge in understanding the drivers of diversity and community structure, as most studies...
T cells are one of the key cells in the immune system. Although they are not the first line of defense against a pathogen, their functions can greatly enhance the phagocytosis and destruction of pathogens as well as the development of antibody responses. Furthermore, even when responding T cells have...
Although IL-4 is a well-characterized multi-functional cytokine, its role as a survival factor in T cells is not completely understood. In an attempt to uncover IL-4-mediated survival, we studied caspase activation in primary mouse T lymphocytes undergoing death by neglect, activation-induced or steroid-induced cell death. Here, we identify the executioner...
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds are well-recognized for their immunosuppressive activity, which is mediated through an intracellular receptor and transcription factor, aryl hydrocarbon receptor (AhR). Laboratory animals exposed to TCDD are less resistant to infection and have severely impaired humoral and cell-mediated immune responses. This dissertation addressed the hypothesis that...
Follicle stimulating hormone (FSH) plays a key role in the ewe’s estrous cycle but understanding its continued importance during pregnancy is not well understood. Researchers have proposed a model theorizing that a cascade of hormones is responsible for pregnancy maintenance. Weems et al. proposed a model for placental progesterone production;...
Vertebrates communicate with one another and coordinate intraspecific reproduction by using a variety of sexually dimorphic signals, such as plumage, ornaments, sounds, and/or scents. These sexual dimorphisms are maintained by physiological factors, typically sex-specific hormones (though see Chapter 3 for an exception). The purpose of the research in this dissertation...
The Northern Rubber Boa (Charina bottae) is a small, secretive boa native to the Pacific Northwest. Despite this being possibly the highest latitude boas and one of only two boas native to the continental U.S., it has received surprisingly little attention. Most of the research on the natural history of...
In diversity combining automatic repeat request (ARQ), erroneous packets are combined together forming a single, more reliable, packet. In this thesis, we give a diversity combining scheme for the m-ary unidirectional channel. A system using the given scheme with a t-unidirectional error detecting code is able to correct up to...
The immune toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) has been studied for over 35 years, but only recently has the profound immune suppression associated with TCDD exposure been linked to induction of regulatory T cells (Tregs). The effects of TCDD are mediated through binding the aryl hydrocarbon receptor (AhR), a ligand-activated transcription...