Index Catalog // ScholarsArchive@OSU

Molecular origins of peptide entrapment in polyethylene oxide layers

Creator:: Wu, Xiangming
Abstract:: A more quantitative understanding of peptide entrapment and elution from otherwise protein-repellent polyethylene oxide (PEO) brush layers will provide direction for development of new strategies for drug storage and delivery. Here we describe criteria for peptide integration and structural change within the PEO brush, and discuss the reversibility of peptide...
Resource Type:: Dissertation
Full Text:: peptide S-WLBU2, and the non-amphiphilic homopolymer poly-L-arginine (PLR). Circular dichroism (CD) was

Bacterial pathogens and associated toxins involved in erythrophore cell aggregation

Creator:: Hutchison, Janine R.
Abstract:: Current detection methods for bacterial contamination rely on structure based detection of proteins and nucleic acids. While these methods are easy to use and reliable, they cannot evaluate the toxicity of a sample and the potential to cause disease. Previously, erythrophore cells derived from Betta splendens had been suggested as...
Resource Type:: Dissertation
Full Text:: single amino acid conversion of alanine to threonine at residue 289 of L2 toxin component of HBL. This

Evaluation of Driver Behavior during Right Turn Maneuvers at Signalized Intersections: Mitigation of Driver-Pedestrian Conflicts with a Right Turn Flashing Yellow Arrow

Creator:: Jashami, Hisham
Abstract:: Accommodating motor vehicles that are turning (left or right) at signalized intersections requires a careful understanding of the safety and efficiency of design and operational variables. Turning vehicles are the primary collision risk for non-motorized road users at signalized intersections. When turning movements need to be controlled, proper driver response...
Resource Type:: Dissertation
Full Text:: drivers were presented with a steady red arrow display as compared to a steady circular red display

Experimental investigation of supercritical heat transfer of carbon dioxide in parallel square microchannels with a single-wall constant heat flux boundary condition

Creator:: Zada, Kyle R.
Abstract:: In the vicinity of the pseudocritical point, supercritical carbon dioxide (sCO₂) undergoes a steep change in properties from “liquid-like” to “gas-like” as it is heated at a constant pressure. At the same time, there is a large spike in specific heat which can yield high heat transfer coefficients and heat...
Resource Type:: Masters Thesis
Full Text:: of supercritical CO2 has primarily focused on circular, uniformly heated channels at relatively low

Binding of bacterial lipopolysaccharide by the cationic amphiphilic peptide WLBU2 at interfaces

Creator:: Ryder, Matthew P.
Abstract:: Passage of blood through a sorbent device for removal of bacteria and endotoxin by specific binding with immobilized, membrane-active, bactericidal peptides holds promise for treating severe blood infections. Peptide insertion in the target membrane and stable binding is desirable, while membrane disruption and release of degradation products to the circulating...
Resource Type:: Dissertation
Full Text:: PmB. Circular dichroism spectra confirmed that WLBU2, which shows disordered structure in aqueous

Alkylation kinetics of the human retinoid X receptor α using cysteine as a local probe

Creator:: Vanegas, Juan Manuel
Abstract:: The unfolding of human retinoid X receptor α in the presence of the denaturant guanidine HCl was studied using stopped-flow absorbance spectroscopy. The protein's four native cysteine residues were mutated to obtain four single-cysteine mutants, each with the other three cysteine residues mutated to alanine. The thiols of these hRXRα...
Resource Type:: Masters Thesis
Full Text:: of the protein. Circular dichroism and tryptophan fluorescence emission were used to determine

Structural and activity characterization of irradiated antimicrobial peptide (WLBU2) for use in blood processing and biomedical applications

Creator:: Cheung, Daniel Y. C.
Abstract:: Sepsis is a life-threatening blood infection which leads to an uncontrolled systemic inflammatory state. In North America alone, sepsis annually afflicts approximately 750,000 individuals and kills 38-50% of these (more than HIV/AIDS, breast cancer, and colon cancer combined). Current treatment involves administration of IV fluids, antibiotics and hemoperfusion, requiring prolonged...
Resource Type:: Honors College Thesis
Full Text:: circular dichroism (CD), and mass spectrometry to characterize chemical and structural changes caused by

Nisin adsorption and function at hydrophobic surfaces coated with the poly[ethylene oxide]-poly[propylene oxide]-poly[ethylene oxide] triblock surfactant Pluronic® F108

Creator:: Tai, Yuan-Ching
Abstract:: The adsorption and elution of the antimicrobial peptide nisin at hydrophobic, silanized silica surfaces coated with the poly[ethylene oxide]-poly[propylene oxide]- poly[ethylene oxide] surfactant Pluronic® F108 was measured in situ, with ellipsometry. While such layers are known to inhibit protein adsorption, nisin was observed to adsorb in multilayer quantities, to an...
Resource Type:: Dissertation
Full Text:: - coated substrates was most pronounced in the presence of blood proteins. Circular dichroism

Conifer regeneration, understory vegetation and artificially topped conifer responses to alternative silvicultural treatments

Creator:: Huff, Tristan
Abstract:: Historically, between 40-60% of the Coast Range of Oregon was comprised of structurally diverse, old forests initiated by disturbances of various spatial scales ranging from thousands of acres (large fires) to the size of a single tree (windthrow). The predominant regeneration method of the past several decades, however, has been...
Resource Type:: Masters Thesis
Full Text:: selection- 33% of volume removed in 0.2 to 1.0 ha circular, square, or strip-shaped gaps. All harvested

Role of post-translational modifications to lens proteins in cataract formation

Creator:: Kim, Yung Hae
Abstract:: Cataract is a leading cause of blindness throughout the world, yet the fundamental biochemical causes are unknown. A rodent model of the biochemical processes is selenite cataract. This cataract shows some of the features of human cataracts such as increased lens calcium, proteolysis of proteins, and insolubilization leading to lens...
Resource Type:: Dissertation
Full Text:: . Urea stability was Redacted for Privacy measured by circular dichroism and fluorescence

ScholarsArchive@OSU

Molecular origins of peptide entrapment in polyethylene oxide layers

Bacterial pathogens and associated toxins involved in erythrophore cell aggregation

Evaluation of Driver Behavior during Right Turn Maneuvers at Signalized Intersections: Mitigation of Driver-Pedestrian Conflicts with a Right Turn Flashing Yellow Arrow

Experimental investigation of supercritical heat transfer of carbon dioxide in parallel square microchannels with a single-wall constant heat flux boundary condition

Binding of bacterial lipopolysaccharide by the cationic amphiphilic peptide WLBU2 at interfaces

Alkylation kinetics of the human retinoid X receptor α using cysteine as a local probe

Structural and activity characterization of irradiated antimicrobial peptide (WLBU2) for use in blood processing and biomedical applications

Nisin adsorption and function at hydrophobic surfaces coated with the poly[ethylene oxide]-poly[propylene oxide]-poly[ethylene oxide] triblock surfactant Pluronic® F108

Conifer regeneration, understory vegetation and artificially topped conifer responses to alternative silvicultural treatments

Role of post-translational modifications to lens proteins in cataract formation

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