Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Creator Demessie, E. Sahle License All rights reserved Commencement Year Unknown

Targeted Nanocarriers for Systemic Delivery of IRAK4 Inhibitors to Inflamed Tissues

Creator:

Park, Youngrong, Korzun, Tetiana, Moses, Abraham S., Singh, Prem, Levasseur, Peter R., Demessie, Ananiya A., Sharma, Kongbrailatpam Shitaljit, Morgan, Terry, Raitmayr, Constanze J., Avila, Uriel, Sabei, Fahad Y., Taratula, Olena R., Marks, Daniel L., and Taratula, Oleh

Abstract:

Persistent and uncontrolled inflammation is the root cause of various debilitating diseases. Given that interleukin-1 receptor–associated kinase 4 (IRAK4) is a critical modulator of inflammation, inhibition of its activity with selective drug molecules (IRAK4 inhibitors) represents a promising therapeutic strategy for inflammatory disorders. To exploit the full potential of this...

Resource Type:

Article

Full Text:

, Peter R. Levasseur, Ananiya A. Demessie, Kongbrailatpam Shitaljit Sharma, Terry Morgan, Constanze J