Novel mucosal vaccines (LL-M2e, LL-HAe, SG-HAe) were constructed from live, non-pathogenic Lactococcus lactis or Streptococcus gordonii that express conserved regions of HA or M2 antigens from avian influenza virus (AIV) A. All three vaccines evoked antigen-specific serum immunoglobulin G (IgG) responses in vaccinated chickens. The addition of the adjuvant cholera...
The myxozoan Ceratonova shasta is an intestinal parasite of salmon and trout that causes ceratomyxosis, a disease characterized by severe inflammation of the intestine that can lead to hemorrhaging, necrosis, and death of the fish host. The parasite is endemic to the Pacific Northwest of the United States and Canada,...
This thesis presents a detailed seismotectonic investigation of the Himalayan region and the Tibetan plateau as part of project HiCLIMB to explore the state of stress and the kinematics of the world’s largest continental collision zone. Using full regional waveforms for moment tensor inversion, source parameters for 107 earthquakes were...
All animals have developed the critical ability to detect, respond to, and detoxify a large array of environmental chemicals and stressors that can cause adverse health effects. Important examples of landmark contaminants around the world are polycyclic aromatic hydrocarbons (PAHs) and dioxins, both of which can act via the aryl...
While there are many more species of reptiles in the tropics than in temperate
latitudes, relatively little is known about the natural history of tropical species of
snakes. Even basic information, such as reproductive ecology and behavior, is lacking. Patterns of reproduction in tropical species differ from patterns in temperate...
During the U.S. military interventions in Nicaragua, the Dominican
Republic, and Haiti between 1915 and 1934, Washington equipped
members of the its armed forces with civil and political powers that
represented a radical departure from the North American military tradition.
This abandonment of tradition decisively contributed to both the
disappointments...
At a time when environmental conditions are rapidly changing, understanding how thermal extremes impact wildlife is imperative to fully understanding the consequences of climate change in natural ecosystems. While many organisms are currently impacted by rapidly warming and more erratic environmental conditions, identifying and investigating model species whose life histories...
This analysis uses data from a larger ethnographic study examining community effects of mobile home park residence on child and youth development to explore the resilient pathways of 8 mothers and maternal guardians in order to understand better how successful adaptation is achieved despite significant threats present throughout the life...
Laboratories around the world are using the zebrafish model for biomedical research and conducting investigations using morphological, physiological, behavioral, and genomic endpoints. All assays provide information, but physiological and behavioral endpoints or phenotypes are a fast way to understand how an animal is responding to its environment. We investigate the...
Around 74 ka, a supervolcano, Toba Caldera in Sumatra, Indonesia erupted, producing the Youngest Toba Tuff and its associated caldera. After this catastrophic eruption, a lake filled the caldera, sedimentation within the lake occurred, and the process known as resurgence began. Today, the resurgent dome, Samosir Island, is uplifted 700...