Index Catalog // ScholarsArchive@OSU

Some potential mechanisms for finely-tuned regulation of phospholipase C-β isozymes : studies of dimerization and phosphatidylinositol 3,4,5-trisphosphate activation

Creator:: Zhang, Yong
Abstract:: Phospholipase C-β (PLC-β) isozymes are key effectors in G protein-coupled signaling pathways. Prior research suggested that some isoforms of PLC-β may exist and function as dimers, but little is known about dimerization of PLC-β. Data from coimmunoprecipitation assays of differentially-tagged PLC-β constructs and sizeexclusion chromatography of native PLC-β support homodimerization...
Resource Type:: Dissertation
Full Text:: Phospholipase C-β Isozymes: Studies of Dimerization and Phosphatidylinositol 3,4,5-Trisphosphate Activation

Ascorbylation- the biological relevance of covalently bound ascorbic acid

Creator:: Kesinger, Nicholas G.
Abstract:: Ascorbic acid, or vitamin C, is well known as a co-factor for proline-hydroxylase and as an anti-oxidant. However, it is also capable of forming covalent bonds, particularly in the role of a nucleophile, henceforth termed 'ascorbylation'. The ascorbylation of electrophiles can occur under physiological conditions. Furthermore, there are a number...
Resource Type:: Dissertation
Full Text:: approved: ___________________________ Dr. Jan F. Stevens Ascorbic acid, or vitamin C, is well known

Regulation of phospholipase C-beta isozymes by calmodulin

Creator:: McCullar, Jennifer Star
Abstract:: Phospholipase C-Jβ (PLCβ) is an important effector enzyme in G-protein-coupled signaling pathways. Activation of PLCβ by Gα and Gβy subunits has been fairly well characterized, but little is known about other protein interactions that may also regulate PLCβ function. A yeast two-hybrid screen of a mouse brain cDNA library with...
Resource Type:: Dissertation
Full Text:: . Title: Regulation of Phoshoplipase C-beta isozymes by Calmodulin A Abstract approved: Theresa M. Filtz

Role of Plc in the germination of Clostridium perfringens food poisoning isolate SM101

Creator:: Bond, Colton B.
Abstract:: Clostridium perfringens is the causative agent of gas gangrene and the 3rd most common cause of type A food borne disease in the United States. Critical to the pathogenicity of C. perfringens is the ability of this bacterium to produce highly resistant, metabolically dormant spores that can resume metabolic function...
Resource Type:: Masters Thesis
Full Text:: disease in the United States. Critical to the pathogenicity of C. perfringens is the ability of this

Part I: Total synthesis of marine macrolide amphidinolide F and synthetic studies toward amphidinolide C; Part II: Computational study on proline sulfonamide-catalyzed aldol reaction

Creator:: Mahapatra, Subham
Abstract:: More than 30 members of the diverse amphidinolide family of biologically active macrolides have been isolated over last three decades. From this family, amphidinolides C and F stand among the most complex and densely functionalized affiliates. Recently, we have accomplished the first total synthesis of amphidinolide F. The all-carbon framework...
Resource Type:: Dissertation
Full Text:: have been isolated over last three decades. From this family, amphidinolides C and F stand among the

Genetic factors that provide adult plant resistance against Puccinia striiformis f. sp. tritici to wheat cultivar 'Stephens' in a multilocation analysis.

Creator:: Vazquez, Maria Dolores
Abstract:: Stripe rust (Puccinia striiformis f. sp. tritici) has been receiving increased attention in the USA since the appearance of more virulent races detected in the past decade. These races caused yield losses even in areas where the disease previously was rarely detected. Host plant resistance is the most cost effective...
Resource Type:: Masters Thesis
Full Text:: f. sp. tritici to Wheat Cultivar ‘Stephens’ in a Multilocation Analysis. Abstract

Quantitative resistance to Puccinia striiformis f. sp. hordei in barley near-isogenic (BISON) lines

Creator:: Richardson, Kelley L.
Abstract:: Quantitative resistance (QR) to disease is usually more durable than qualitative resistance, but its genetic basis is not well understood. We used the barley/barley stripe rust pathosystem as a model for the characterization of the QR phenotype and associated genomic regions. As an intermediate step in the preparation of near-isogenic...
Resource Type:: Dissertation
Full Text:: September 25, 2006. Title: Quantitative Resistance to Puccinia striiformis f. sp. hordei in Barley Near

SLC23A1, the gene encoding sodium-dependent vitamin C transport protein 1 (SVCT1) : regulation of transcription and its functional consequences

Creator:: Michels, Alexander Johannes
Abstract:: Vitamin C is an essential component of the human diet. Uptake of vitamin C in the cell is regulated by the function of sodium-dependent vitamin C transporters (SVCTs). SVCT1 (encoded by the SLC23A1 gene) is expressed in the colon, liver and kidney, where it plays a vital role in determining...
Resource Type:: Dissertation
Full Text:: Biophysics presented on September 19, 2007. Title: SLC23A1, the Gene Encoding Sodium-Dependent Vitamin C

Geneticist L.C. Dunn : politics, activism, and community

Creator:: Gormley, Melinda (Melinda Brooke)
Abstract:: L. C. Dunn (1893-1974) spent most of his scientific career conducting research in developmental genetics as a member of the Zoology Department at Columbia University in the City of New York. He had an accomplished scientific career researching mutations in mice, which earned him respect from other geneticists and scientists....
Resource Type:: Dissertation
Full Text:: : Mary Jo Nye L. C. Dunn (1893-1974) spent most of his scientific career conducting research

C-SHIFT, Quantile Theory, and Assessing Monotonicity

Creator:: Logan, Paul R.
Abstract:: DNA microarray technology is a powerful tool for analyzing patterns in gene expression data for thousands of genes. Due to a number of systematic variations in microarray experiments, the raw gene expression data is often obfuscated by undesirable technical noises. Various normalization techniques were designed in an attempt to remove...
Resource Type:: Dissertation
Full Text:: (Cα), i.e., we estimate â by α∗ = argmin‖Cα‖F . The assumption is based on the observation that a

ScholarsArchive@OSU

Some potential mechanisms for finely-tuned regulation of phospholipase C-β isozymes : studies of dimerization and phosphatidylinositol 3,4,5-trisphosphate activation

Ascorbylation- the biological relevance of covalently bound ascorbic acid

Regulation of phospholipase C-beta isozymes by calmodulin

Role of Plc in the germination of Clostridium perfringens food poisoning isolate SM101

Part I: Total synthesis of marine macrolide amphidinolide F and synthetic studies toward amphidinolide C; Part II: Computational study on proline sulfonamide-catalyzed aldol reaction

Genetic factors that provide adult plant resistance against Puccinia striiformis f. sp. tritici to wheat cultivar 'Stephens' in a multilocation analysis.

Quantitative resistance to Puccinia striiformis f. sp. hordei in barley near-isogenic (BISON) lines

SLC23A1, the gene encoding sodium-dependent vitamin C transport protein 1 (SVCT1) : regulation of transcription and its functional consequences

Geneticist L.C. Dunn : politics, activism, and community

C-SHIFT, Quantile Theory, and Assessing Monotonicity

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