Index Catalog // ScholarsArchive@OSU

Detection, biosynthesis, and structural investigations of naturally occurring alkynes and other microbial metabolites

Creator:: Back, Daniel C.
Abstract:: Natural products have long been an important source of resources for humans. Many of these compounds possess unique chemical structures and potent biological properties. By targeting natural products with specific chemical properties, we can gain a better understanding of the roles these compounds play in the environment and their interactions...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE DISSERTATION OF Daniel C

Aiding Plants and Humans by Targeting Virulence Strategies: Investigation of key protein residues involved in toxoflavin production

Creator:: Justen, Savannah F.
Abstract:: Toxoflavin, a toxic secondary metabolite produced by a variety of bacteria, has been implicated as a causative agent in food poisoning and a virulence factor in phytopathogenic bacteria. This toxin is produced by the tox operon in Burkholderia glumae, in which the encoded protein, ToxD, was previously characterized as essential...
Resource Type:: Honors College Thesis
Full Text:: approved: Benjamin Philmus Toxoflavin, a toxic secondary metabolite produced by a variety of bacteria

The role of sigma factors in production of cyanobacterial natural products: Escherichia coli as a heterologous expression host

Creator:: Wells, Kaitlyn N.
Abstract:: Cyanobacteria represent an underexploited source of bioactive natural products of interest to the pharmaceutical industry. Lack of development of these compounds as drug leads is due mainly to myriad practical problems with the producing strains including long doubling times, genetic intractability, and low compound yields. Previous attempts at heterologous expression...
Resource Type:: Honors College Thesis
Full Text:: approved:_____________________________________________________ Benjamin Philmus Cyanobacteria

Structure and Dynamics of the Canine (Canis familiaris) Nasal Microbiome

Creator:: Knorr, Elizabeth
Abstract:: The diverse community of bacteria living within and on host organisms, known as the microbiome, has an important role in maintaining host health. Dysbiosis, known as a change in the healthy community of the microbiome, has been associated with a number of diseases across host organisms and body sites including...
Resource Type:: Dissertation
Full Text:: Microbiome Abstract approved: ______________________________________________________ Benjamin D

Coastal Soil and Structure Behavior during Earthquake-Tsunami Multi-Hazards

Creator:: Qiu, Yingqing
Abstract:: Coastal multi-hazards, i.e., earthquakes followed by tsunamis, induce severe damage to coastal infrastructure. The multi-hazards can cause soil liquefaction, which is one of the major concerns for evaluating sediments transport potential and structure failure mechanisms. The objectives for this work is threefold. First, to build and validate a soil numerical...
Resource Type:: Dissertation
Full Text:: and Structure Behavior during Earthquake-Tsunami Multi-Hazards Abstract approved: H. Benjamin Mason

Pore Water Pressure Response in Soil During Tsunami Loading : Numerical Formulation and Experimentation

Creator:: Abdollahi, Abbas
Abstract:: Tsunami loading can cause sediment instability, which can compromise the structural integrity of coastal buildings and infrastructure. To understand the process by which a tsunami can cause sediment instability, it is necessary to understand how the pore water pressure in the soil changes during tsunami loading. Tsunami run-up causes the...
Resource Type:: Dissertation
Full Text:: approved: H. Benjamin Mason Tsunami loading can cause sediment instability, which can compromise the

Tsunami-induced Soil Instability

Creator:: Fischer, Rachael Marie
Abstract:: Recent tsunami field surveys from the 2011 Great East Japan Earthquake and Tsunami have recorded numerous examples of tsunami-induced soil instability: significant scour around foundations, foundation failure of piles, and other damage caused by liquefaction. From the observations of soil instability leading to the failure of critical coastal structures, it...
Resource Type:: Masters Thesis
Full Text:: Instability Abstract approved: H. Benjamin Mason Recent tsunami field surveys from the 2011 Great East

Near-Surface Response of Beach Sand : An Experimental Investigation

Creator:: Adams, Rachel Katie
Abstract:: The near-surface region of a coastal sediment bed is complex and dynamic. At some sites, near-surface sediment deposits are susceptible to extreme events, such as tsunamis or other large overflows, which induce high shear stresses on the sediment bed. The specific properties of sediment beds subjected to such extreme loading...
Resource Type:: Masters Thesis
Full Text:: Response of Beach Sand: An Experimental Investigation Abstract approved: H. Benjamin Mason Keywords

Adjacent structure response sensitivity to seismic events using the direct differentiation method

Creator:: White, William S.
Abstract:: The response of adjacent structural systems to earthquake motions is investigated using the finite element framework OpenSees. Results of sensitivity analyses demonstrate that structural response quantities can increase in either or both of the adjacent structures for specific configurations. The structural models used include steel moment-resisting frames and rigid shear...
Resource Type:: Masters Thesis
Full Text:: . Benjamin Mason The response of adjacent structural systems to earthquake motions is investigated using

Recombinant vaccines against infectious hematopoietic necrosis virus : bacterial systems for vaccine production and delivery

Creator:: Simon, Benjamin E.
Abstract:: Several systems were examined for the production and delivery of recombinant vaccines for fish. C. crescentus was employed to produce a fragment of the IHNV glycoprotein. When administered by injection to 0.5 gram rainbow trout (Oncorhynchus mykiss), one of the fusion proteins (184 amino acids of the IHNV glycoprotein fused...
Resource Type:: Dissertation
Full Text:: Benjamin E. Simon for the degree of Doctor of Philosophy in Microbiology presented on October 9, 2001

ScholarsArchive@OSU

Detection, biosynthesis, and structural investigations of naturally occurring alkynes and other microbial metabolites

Aiding Plants and Humans by Targeting Virulence Strategies: Investigation of key protein residues involved in toxoflavin production

The role of sigma factors in production of cyanobacterial natural products: Escherichia coli as a heterologous expression host

Structure and Dynamics of the Canine (Canis familiaris) Nasal Microbiome

Coastal Soil and Structure Behavior during Earthquake-Tsunami Multi-Hazards

Pore Water Pressure Response in Soil During Tsunami Loading : Numerical Formulation and Experimentation

Tsunami-induced Soil Instability

Near-Surface Response of Beach Sand : An Experimental Investigation

Adjacent structure response sensitivity to seismic events using the direct differentiation method

Recombinant vaccines against infectious hematopoietic necrosis virus : bacterial systems for vaccine production and delivery

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