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  • Induced Mutation for Improving Cascade and Centennial Hop

    Creator:
    Getty, Brooke A.
    Abstract:
    Hop, Humulus lupulus L. is a dioecious perennial species. The female hop plant produces flowers that mature into ‘cones’ which are used as a raw material in the beer brewing process to impart bitterness, flavor, and aroma. The craft beer industry in the current global beer market continues to experience...
    Resource Type:
    Masters Thesis
    Full Text:
    Induced Mutation for Improving Cascade and Centennial Hop by Brooke A. Getty A THESIS submitted to

  • Ignition of Fuel Beds by Firebrands

    Creator:
    Bean, Derek R.
    Abstract:
    The severity of wildfires around the globe is increasing. At the same time, urban development is expanding outward into areas where severe fires occur. There is an increased risk of home loss to fires in areas where severe fires and urban expansion meet. Ignition of homes or nearby fuel is...
    Resource Type:
    Dissertation
    Full Text:
    surrounding foliage [21] and moisture content of the foliage [22] which introduces significant variability in

  • Exploring Asian and Asian American Specific Body Mass Index Cut-Points

    Creator:
    Lee, Lauren J.
    Abstract:
    Background: Body Mass Index (BMI) is used as a quick and inexpensive tool to measure populations at risk for a number of metabolic and chronic conditions. In part due to its simplicity, BMI has been criticized for its inaccurate prediction concerning health outcomes. Due to the diversity in the United...
    Resource Type:
    Honors College Thesis
    Full Text:
    measure populations at risk for a number of metabolic and chronic conditions. In part due to its

  • Functional analysis of novel β-catenin mutants

    Creator:
    Al-Fageeh, Mohamed B.
    Abstract:
    β-catenin is a multi functional protein that is involved in cell-cell adhesion and cell signaling. In non-stimulated cells, β-catenin is tightly down-regulated by GSK-3β-dependent phosphorylation at Ser and Thr residues, followed by rapid ubiquitination and proteasomal degradation. It is well established that mutations within the regulatory GSK-3β region lead to...
    Resource Type:
    Masters Thesis
    Full Text:
    . One mutation occurs in the oncogene K-ras and other mutations inactivate the tumor suppressor genes

  • Vaccine beliefs of complementary and alternative medical (CAM) providers in Oregon

    Creator:
    Bean, Sandra J.
    Abstract:
    Health care providers, including complementary and alternative medical (CAM) practitioners, exert a significant influence on parental pediatric vaccination decisions. Use of CAM therapies is increasing in Oregon. Concomitantly, there has been a decade-long increase in parental vaccine refusal in Oregon, rising from 1 to 5 percent from 2000-2009. For example,...
    Resource Type:
    Dissertation
    Full Text:
    Beliefs of Complementary and Alternative Medical (CAM) Providers in Oregon Abstract approved

  • Characterization of Neurospora crassa and Fusarium graminearum mutants defective in repeat-induced point mutation

    Creator:
    Pomraning, Kyle R.
    Abstract:
    Mutation of repetitive DNA by repeat-induced point mutation (RIP) is a process that occurs in many filamentous fungi of the Ascomycota during the sexual cycle. Concurrently, direct DNA repeats are often deleted by homologous recombination at high frequency during the sexual cycle. Thus, the processes of RIP and deletion compete...
    Resource Type:
    Dissertation
    Full Text:
    crassa and Fusarium graminearum Mutants Defective in Repeat-induced Point Mutation by Kyle R

  • On the limits of mutation analysis

    Creator:
    Gopinath, Rahul
    Abstract:
    Mutation analysis is the gold standard for evaluating test-suite adequacy. It involves exhaustive seeding of all small faults in a program and evaluating the effectiveness of test suites in detecting these faults. Mutation analysis subsumes numerous structural coverage criteria, approximates fault detection capability of test suites, and the faults produced...
    Resource Type:
    Dissertation
    Full Text:
    on the relation between mutations introduced by mutation analysis and real faults. In fact, using a

  • Reversion reporters in Arabidopsis thaliana to detect all six base substitution pathways

    Creator:
    Bollmann, Stephanie R.
    Abstract:
    Maintaining genome integrity is essential for an organism, as mutation accumulation can lead to cancer, reduced fitness, and heritable diseases in offspring. Therefore the study of mutations, how they are induced, and how they are prevented is vital. Biomonitor systems are useful for understanding the relevant biological effects of a...
    Resource Type:
    Dissertation
    Full Text:
    of mutations, how they are induced, and how they are prevented is vital. Biomonitor systems are

  • Protein-protein interactions in the bacteriophage T4 dNTP synthetase complex

    Creator:
    Shen, Rongkun
    Abstract:
    The enzymes of dNTP synthesis in T4 infection associate to form a multienzyme complex, the T4 dNTP synthetase complex, facilitating the flow of metabolites en route to dNTPs, and their subsequent flow into DNA. Study of protein-protein interactions helps one to understand how the enzymes in the complex are organized...
    Resource Type:
    Dissertation
    Full Text:
    DISSERTATION OF Rongkun Shen for the degree of Doctor of Philosophy in Biochemistry and Biophysics

  • Pathogenic Mechanisms of Cancer Causing hMLH1 Mutations

    Creator:
    O'Donnell, Edmond Francis
    Abstract:
    DNA mismatch repair (MMR) is an evolutionary conserved process that functions to maintain genomic integrity through the correction of mismatches that have escaped proofreading. Mutations in the MMR gene Mlh1 are associated with approximately 50% of all cases of Lynch syndrome, a hereditary predisposition to colorectal cancer, through varying and...
    Resource Type:
    Honors College Thesis
    Full Text:
    spontaneous and DNA damage-induced mutation rates, reduced apoptotic responses, and is associated with