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Characterization of the Sodium Transporting NADH:Quinone Oxidoreductase (NQR) in Vibrio cholerae

Creator:

Fassio, Sara R.

Abstract:

Vibrio cholerae is the causative agent of cholera, a serious diarrheal disease in developing countries. V. cholerae has a unique redox driven respiration-linked sodium pump, Na⁺ translocating NADH:quinone oxidoreductase (NQR). Several reports previously showed that NQR plays an important role in virulence, metabolism, and sodium homeostasis of V. cholerae. This...

Resource Type:

Honors College Thesis

Full Text:

. Yusuke Minato for his constant support and encouragement, for fostering an interest in research, and
Molecular and genetic assessment of selected antiporters and methyl-accepting chemotaxis proteins in Vibrio cholerae

Creator:

Quinn, Matthew J.

Abstract:

The pathogen Vibrio cholerae uses cations as a primary currency of virulence and environmental persistence, using gradients of those cations to move, acquire nutrients, and control virulence gene expression. An understanding of the overlapping roles of bioenergetics and chemotaxis in the virulence and environmental survival of V. cholerae issues from...

Resource Type:

Dissertation

Full Text:

source of inspiration and innovation, who spared valuable time to mentor the author. Yusuke Minato has