Long-standing research has highlighted the critical role of physical and outdoor activities for children’s health and wellbeing. During the COVID-19 pandemic, children and youth around the world experienced heightened stress and poor mental health, which coincided with a decrease in active play and increase in screen-based activities. This work aims...
Impedance measurements are increasingly demanded in modern CMOS sensing systems as impedance is the most common electrical signal obtained from sensors, delivering physical, chemical and biomedical quantity changes. Impedance sensing for wide interested frequency, broad dynamic range, and various sensor interfaces has numerous challenges, especially targeted in CMOS miniaturization with...
The primary purpose of this study was to try to (1) provide information on the chemical nature, including turbidity formation, of polygalacturonic acid in different concentrations of NaCl solution. (2) use turbidity formation characteristics to develop an assay for determining the activities polygalacturonic acid depolymerases by using a polyelectrolyte. (3)...
Oceanic uptake of rising anthropogenic CO₂ emissions has caused the emergence of ocean acidification as a major threat to marine ecosystems worldwide. Along eastern boundary current systems, seawater is naturally acidified due to coastal upwelling of low pH seawater from depth. Compounded by ocean acidification, upwelling regions are expected to...
Vibrio parahaemolyticus is the leading cause of foodborne illnesses associated with seafood consumption. Consuming raw or undercooked seafood contaminated with V. parahaemolyticus can result in development of acute gastroenteritis with symptoms of nausea, vomiting, abdominal cramping and watery diarrhea within 24 hours of infection. Illness is usually self-limited and lasts...
The enzymes of dNTP synthesis in T4 infection associate to form a multienzyme complex, the T4 dNTP synthetase complex, facilitating the flow of metabolites en route to dNTPs, and their subsequent flow into DNA. Study of protein-protein interactions helps one to understand how the enzymes in the complex are organized...
The experiments explained in this Honors thesis are focused on finding a cellular model for analyzing Bcl11b, a transcription factor dysregulated in 20% of cases of T-cell Acute Lymphoblastic Leukemia (T-ALL). Acute Lymphoblastic Leukemia is the most common childhood cancer. Because T-ALL is a result of incorrect thymocyte development, research...
Protein secondary structure prediction plays a pivotal role in predicting protein folding in three-dimensions. Its task is to assign each residue one of the three secondary structure classes helix, strand, or random coil. This is an instance of the problem of sequential supervised learning in machine learning. This thesis describes...
High speed and high resolution analog-to-digital converter is a key building block for broadband wireless communications, high definition video applications, medical images and so on. By leveraging the down scaling of the latest CMOS technology and the noise shaping properties, delta-sigma (ΔΣ) ADCs are able to achieve wide-band operation and...
Knowledge workers are struggling in the information flood. There is a growing interest in intelligent desktop environments that help knowledge workers organize their daily life. Intelligent desktop environments allow the desktop user to define a set of “activities” that characterize the user’s desktop work. These environments then attempt to identify...