The primary goal of my study was to evaluate the effects of high dietary vitamin E on the rodent skeleton. The outcomes from my study assess the impact of high intakes of vitamin E and increased concentrations of its metabolite, carboxy ethyl hydroxy chromanol (CEHC), on bone turnover and skeletal...
The impacts of climate change are being observed worldwide. However, some regions and context specific situations make particular areas more vulnerable to the impacts than others. Alaska’s Kenai River Watershed (KRW) is on the front lines of climate change and may be especially vulnerable to the impacts due to distinct...
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Dr. David Turner, Major Professor, Department of Forest Ecosystem and Society
An inventor seeks to leverage his unique means in order to create and commercially exploit new technologies. Until new technologies are sufficiently developed, they have the theoretical potential for commercial exploitation in a wide range of markets. Those opportunities are limited by physical bounds that are often only discovered through...
The primary goal of my studies was to elucidate the mechanisms for the well-recognized interaction between two nutrients, vitamins E and K. The outcomes from my studies assess mechanisms for adverse effects of vitamin E and provide novel information on mechanisms for vitamin K homeostasis. These findings will provide information...
Health officials have recently been sounding the alarm that depression will soon
surpass many of the major medical conditions in causing disability among adults. Recent
demographic and health trends are generating public health concern about depression.
First, the prevalence of chronic conditions has dramatically increased over the last several
generations....
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R. Turner Goins
Health officials have recently been sounding the alarm that depression
The reduction in mechanical load imparted on the body during spaceflight presents unique physiological challenges. One detrimental and seemingly unavoidable response to microgravity is rapid bone loss. This adaptation is hazardous not only to astronaut health, but to the success of long-duration exploration-class missions. Skeletal adaptation to spaceflight in astronauts...
Background: Alcohol is a nonessential nutrient widely consumed throughout the world. Chronic alcohol abuse is associated with numerous adverse skeletal effects. However, prior to this study, the effects of alcohol abuse on intracortical bone remodeling in an animal model had not been investigated. Reduced intracortical bone remodeling could impair repair...
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Urszula T. Iwaniec Russell T. Turner
Background: Alcohol is a nonessential nutrient
Post-menopausal women are at an increased risk for osteoporosis due to increased
bone resorption associated with estrogen deficiency. Subcutaneous administration of leptin, a
hormone produced primarily by adipocytes, attenuates bone loss in the ovariectomized (ovx)
rat, an animal model for post-menopausal bone loss. Leptin has both direct peripheral and
indirect...
The objectives of this research is to advance human health by evaluating interventions to minimize the detrimental effects of acute whole body gamma irradiation on bone metabolism, bone architecture and bone reconstruction using a mouse model. Total body irradiation (TBI) followed by adoptive transfer of bone marrow from donor animals...
Insoluble surfactants are unique molecules that have the ability to manipulate interfacial properties, becoming useful in numerous applications such as detergents, wetting agents, emulsifiers, foaming agents, dispersants, and more. Interfacial rheology is a field that attempts to characterize the flow properties of insoluble surfactants by exerting a stress on the...