Index Catalog // ScholarsArchive@OSU

Age-related decrease in resilience against acute redox cycling agents: Critical role of declining GSH-dependent detoxification capacity

Creator:: Thomas, Nicholas O.
Abstract:: Over the past century, life expectancy in the United States has dramatically increased leading to an increasingly aging population with people reaching, and spending more years in ‘old age’. While this unprecedented shift in population demographics represents great strides for humanity, it is not without cost. One consequence of longer...
Resource Type:: Dissertation

Boosting Intracellular Delivery of mRNA Therapeutics

Creator:: Patel, Siddharth D.
Abstract:: Intracellular delivery of mRNA holds great potential for vaccine and therapeutic discovery and development. This is realized by the preeminent role mRNA is playing in the record-breaking pace of SARS-CoV-19 vaccine development. Recent advances in chemical modifications of mRNA have enabled high-efficiency gene expression with superior spatiotemporal control while eliminating...
Resource Type:: Dissertation

Characterization of the pathogenicity and phylogeny of members of the Rhodococcus genus

Creator:: Creason, Allison L.
Abstract:: Plant pathogenic Rhodococcus species are persistent pathogens able to cause severe growth deformities on a large range of hosts. The most well studied species, R. fascians is predicted by current models to synthesize a mixture of cytokinins that act to directly perturb the hosts' hormone balances, which results in abnormal...
Resource Type:: Dissertation

Concurrent error detection

Creator:: Gorshe, Steven Scott
Abstract:: Concurrent error detection (CED) is the detection of errors or faults in a circuit or data path concurrent with normal operation of that circuit. The general approach for CED is to calculate a check symbol for the inputs to the circuit under operation, predict the check symbol that will result...
Resource Type:: Dissertation

Continuous Flow Microwave-Assisted Synthesis as a Potentially Scalable Nanomanufacturing Approach

Creator:: Albuquerque, Gustavo Henrique T. C. de
Abstract:: The development of nanomaterials and the potential enhancement of their chemical, mechanical, electrical, and optical properties have led to the investigation of methods for their synthesis at lower cost with enhanced performance for next generation devices. Along with the pursuit of new materials that exhibit properties of interest, industry requires...
Resource Type:: Dissertation

Deciphering the Function of New Gonorrhea Vaccine Candidates in Cell Envelope Homeostasis

Creator:: Baarda, Benjamin I.
Abstract:: Neisseria gonorrhoeae is the sexually transmitted pathogen responsible for millions of cases of gonorrhea worldwide each year. Rapidly-spreading antibiotic resistance is diminishing the ability to effectively treat a disease with significant consequences to female and male reproductive health, as well as to neonatal well-being. A protective vaccine has the potential...
Resource Type:: Dissertation

Effects of small molecule ligands on the conformational dynamics of the Farnesoid X Receptor ligand binding domain (FXR-LBD)

Creator:: Yang, Liping
Abstract:: The Farnesoid X Receptor (FXR) is a member of the nuclear receptor superfamily of transcription factors that plays a key role in the regulation of bile acids, lipid and glucose metabolisms. The regulative function of FXR is governed by conformational changes of the ligand binding domain (LBD) upon ligand binding....
Resource Type:: Dissertation
Full Text:: group-mates, Shin-Cheng Tzeng and Sasidhar Nirudodhi for their kind advice. I also wish to thank other

Electric Machine Capability Characterization for Actuators in Disaster Response Robots

Creator:: Li, Qianyun
Abstract:: Disaster response robots need to be simultaneously able to survive extreme environment and complete the mission efficiently and robustly. One of the determinants is the performance of the actuators in each joint, which drive the robot to the desired motion accurately. In robotics society, people usually build their robots directly...
Resource Type:: Masters Thesis

Energy-efficient, short-range ultra-wideband radio transceivers

Creator:: Hu, Changhui
Abstract:: Short-range wireless communications continually attract interest from both industry and academia, and it is changing our life in every aspect in the last decade. The design of wireless transceivers is the bottleneck for variety applications, due to RF modeling inaccuracy, stringent FCC regulations over the transmitted power spectrum, interference, multi-path...
Resource Type:: Dissertation
Full Text:: , Jiao Cheng, Nariman Moezzi, Lingli Xia, Rui Bai, Chao Ma, Eric Donkoh, Ryan Albright, and Ben Goska

Evolutionary Approach to Efficient Provisioning and Self-organization in Wireless Sensor Networks (WSN)

Creator:: Khanna, Rahul, 1966-
Abstract:: Advances in low-power digital integration and microelectro-mechanical systems (MEMS) have paved the way for micro-sensors. These sensors are equipped with data processing capabilities along with sensory circuits. Sensor data are processed on these individual sensors and transmitted to the target (sink). Lowcost integration and small sizes of these sensors have...
Resource Type:: Dissertation

ScholarsArchive@OSU

Age-related decrease in resilience against acute redox cycling agents: Critical role of declining GSH-dependent detoxification capacity

Boosting Intracellular Delivery of mRNA Therapeutics

Characterization of the pathogenicity and phylogeny of members of the Rhodococcus genus

Concurrent error detection

Continuous Flow Microwave-Assisted Synthesis as a Potentially Scalable Nanomanufacturing Approach

Deciphering the Function of New Gonorrhea Vaccine Candidates in Cell Envelope Homeostasis

Effects of small molecule ligands on the conformational dynamics of the Farnesoid X Receptor ligand binding domain (FXR-LBD)

Electric Machine Capability Characterization for Actuators in Disaster Response Robots

Energy-efficient, short-range ultra-wideband radio transceivers

Evolutionary Approach to Efficient Provisioning and Self-organization in Wireless Sensor Networks (WSN)

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