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Role of myosin heavy chain polymorphism in differential susceptibility of muscle fibers to eccentric contraction

Creator:

Choi, Seung Jun

Abstract:

Relationships between myosin heavy chain (MHC) isoform content and eccentric-induced damage were investigated in chemically skinned muscle fiber segments. Fibers were subjected to an eccentric contraction standardized for strain magnitude (0.25 fiber length) and velocity (0.50 maximal shortening velocity). Fiber MHC isoform content was identified by SDS-PAGE. Pre- to post-eccentric...

Resource Type:

Dissertation

Full Text:

linear regression The first study utilized vastus lateralis (VL) fibers from young human subjects