Index Catalog // ScholarsArchive@OSU

Endosperm Tolerance of Paternal Aneuploidy Allows Radiation Hybrid Mapping of the Wheat D-Genome and a Measure of γ Ray-Induced Chromosome Breaks

Creator:: Tiwari, Vijay K., Riera-Lizarazu, Oscar, Gunn, Hilary L., Lopez, KaSandra, Iqbal, M. Javed, Kianian, Shahryar F., and Leonard, Jeffrey M.
Abstract:: Physical mapping and genome sequencing are underway for the ≈17 Gb wheat genome. Physical mapping methods independent of meiotic recombination, such as radiation hybrid (RH) mapping, will aid precise anchoring of BAC contigs in the large regions of suppressed recombination in Triticeae genomes. Reports of endosperm development following pollination with...
Resource Type:: Article
Full Text:: as a potential source of RH mapping germplasm. Here, we report a novel approach to construct RH based

Recruitment, Growth and Mortality of an Antarctic Hexactinellid Sponge, Anoxycalyx joubini

Creator:: Dayton, Paul K., Kim, Stacy, Jarrell, Shannon C., Oliver, John S., Hammerstrom, Kamille, Fisher, Jennifer L., O'Connor, Kevin, Barber, Julie S., Robilliard, Gordon, Barry, James, Thurber, Andrew R., and Conlan, Kathy
Abstract:: Polar ecosystems are sensitive to climate forcing, and we often lack baselines to evaluate changes. Here we report a nearly 50-year study in which a sudden shift in the population dynamics of an ecologically important, structure-forming hexactinellid sponge, Anoxycalyx joubini was observed. This is the largest Antarctic sponge, with individuals...
Resource Type:: Article
Full Text:: baselines to evaluate changes. Here we report a nearly 50-year study in which a sudden shift in the

Lymphocytic Choriomeningitis Virus Infection in FVB Mouse Produces Hemorrhagic Disease

Creator:: Schnell, Frederick J., Sundholm, Sarah, Crumley, Stacy, Iversen, Patrick L., and Mourich, Dan V.
Abstract:: The viral family Arenaviridae includes a number of viruses that can cause hemorrhagic fever in humans. Arenavirus infection often involves multiple organs and can lead to capillary instability, impaired hemostasis, and death. Preclinical testing for development of antiviral or therapeutics is in part hampered due to a lack of an...
Resource Type:: Article
Full Text:: FVB challenged mice, extending this model to more widely available immunological tools. This report

Long-term individual sighting history database: an effective tool to monitor satellite tag effects on cetaceans

Creator:: Gendron, D., Serrano, I. Martinez, de la Cruz, A. Ugalde, Calambokidis, J., and Mate, B.
Abstract:: During the last 3 decades, tagging technology has been used to study different aspects of cetacean ecology. Tags implanted in animal’s blubber, muscle and surrounding tissue have produced successful results, providing information on long-term movements. However, apart from the reports of ‘divots’ (depressions) and swelling at the tag sites in...
Resource Type:: Article
Full Text:: adult female blue whale over a period of 16 yr (1995 to 2011). This report describes the swelling

Coibamide A Induces mTOR-Independent Autophagy and Cell Death in Human Glioblastoma Cells

Creator:: Hau, Andrew M., Greenwood, Jeffrey A., Lohr, Christiane V., Serrill, Jeffrey D., Proteau, Philip J., Ganley, Ian G., McPhail, Kerry L., and Ishmael, Jane E.
Abstract:: Coibamide A is an N-methyl-stabilized depsipeptide that was isolated from a marine cyanobacterium as part of an International Cooperative Biodiversity Groups (ICBG) program based in Panama. Previous testing of coibamide A in the NCI in vitro 60 cancer cell line panel revealed a potent anti-proliferative response and "COMPARE-negative" profile indicative...
Resource Type:: Article
Full Text:: mechanism of action. We report that coibamide A is a more potent and efficacious cytotoxin than was

Malonate Inhibits Virulence Gene Expression in Vibrio cholerae

Creator:: Minato, Yusuke, Fassio, Sara R., and Häse, Claudia C.
Abstract:: We previously found that inhibition of the TCA cycle, either through mutations or chemical inhibition, increased toxT transcription in Vibrio cholerae. In this study, we found that the addition of malonate, an inhibitor of succinate dehydrogenase (SDH), decreased toxT transcription in V. cholerae, an observation inconsistent with the previous pattern...
Resource Type:: Article
Full Text:: Undergraduate Research Program. The funders had no role in study design, data collection and analysis, decision

BCL11B Regulates Epithelial Proliferation and Asymmetric Development of the Mouse Mandibular Incisor

Creator:: Kyrylkova, Kateryna, Kyryachenko, Sergiy, Biehs, Brian, Klein, Ophir, Kioussi, Chrissa, and Leid, Mark
Abstract:: Mouse incisors grow continuously throughout life with enamel deposition uniquely on the outer, or labial, side of the tooth. Asymmetric enamel deposition is due to the presence of enamel-secreting ameloblasts exclusively within the labial epithelium of the incisor. We have previously shown that mice lacking the transcription factor BCL11B/CTIP2 (BCL11B...
Resource Type:: Article
Full Text:: hereafter) exhibit severely disrupted ameloblast formation in the developing incisor. We now report that

Aggregation of Sea Urchin Phagocytes Is Augmented In Vitro by Lipopolysaccharide

Creator:: Majeske, Audrey J., Bayne, Christopher J., and Smith, L. Courtney
Abstract:: Development of protocols and media for culturing immune cells from marine invertebrates has not kept pace with advancements in mammalian immune cell culture, the latter having been driven by the need to understand the causes of and develop therapies for human and animal diseases. However, expansion of the aquaculture industry...
Resource Type:: Article
Full Text:: understand the causes of disease outbreaks and to develop means to avoid and remedy epidemics. We report a

Circadian Regulation of Glutathione Levels and Biosynthesis in Drosophila melanogaster

Creator:: Beaver, Laura M., Klichko, Vladimir I., Chow, Eileen S., Kotwica-Rolinska, Joanna, Williamson, Marisa, Orr, William C., Radyuk, Svetlana N., and Giebultowicz, Jadwiga M.
Abstract:: Circadian clocks generate daily rhythms in neuronal, physiological, and metabolic functions. Previous studies in mammals reported daily fluctuations in levels of the major endogenous antioxidant, glutathione (GSH), but the molecular mechanisms that govern such fluctuations remained unknown. To address this question, we used the model species Drosophila, which has a...
Resource Type:: Article
Full Text:: survivorship under normal and stress conditions. In the current study we report that the GSH concentrations in

Roles of brca2 (fancd1) in Oocyte Nuclear Architecture, Gametogenesis, Gonad Tumors, and Genome Stability in Zebrafish

Creator:: Rodriguez-Mari, Adriana, Wilson, Catherine, Titus, Tom A., Canestro, Cristian, BreMiller, Ruth A., Yan, Yi-Lin, Nanda, Indrajit, Johnston, Adam, Kanki, John P., Gray, Erin M., He, Xinjun, Spitsbergen, Jan, Schindler, Detlev, and Postlethwait, John H.
Abstract:: Mild mutations in BRCA2 (FANCD1) cause Fanconi anemia (FA) when homozygous, while severe mutations cause common cancers including breast, ovarian, and prostate cancers when heterozygous. Here we report a zebrafish brca2 insertional mutant that shares phenotypes with human patients and identifies a novel brca2 function in oogenesis. Experiments showed that...
Resource Type:: Article
Full Text:: cancers including breast, ovarian, and prostate cancers when heterozygous. Here we report a zebrafish

ScholarsArchive@OSU

Endosperm Tolerance of Paternal Aneuploidy Allows Radiation Hybrid Mapping of the Wheat D-Genome and a Measure of γ Ray-Induced Chromosome Breaks

Recruitment, Growth and Mortality of an Antarctic Hexactinellid Sponge, Anoxycalyx joubini

Lymphocytic Choriomeningitis Virus Infection in FVB Mouse Produces Hemorrhagic Disease

Long-term individual sighting history database: an effective tool to monitor satellite tag effects on cetaceans

Coibamide A Induces mTOR-Independent Autophagy and Cell Death in Human Glioblastoma Cells

Malonate Inhibits Virulence Gene Expression in Vibrio cholerae

BCL11B Regulates Epithelial Proliferation and Asymmetric Development of the Mouse Mandibular Incisor

Aggregation of Sea Urchin Phagocytes Is Augmented In Vitro by Lipopolysaccharide

Circadian Regulation of Glutathione Levels and Biosynthesis in Drosophila melanogaster

Roles of brca2 (fancd1) in Oocyte Nuclear Architecture, Gametogenesis, Gonad Tumors, and Genome Stability in Zebrafish

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