Index Catalog // ScholarsArchive@OSU

The Genome of Tolypocladium inflatum: Evolution, Organization, and Expression of the Cyclosporin Biosynthetic Gene Cluster

Creator:: Bushley, Kathryn E., Raja, Rajani, Jaiswal, Pankaj, Cumbie, Jason S., Nonogaki, Mariko, Boyd, Alexander E., Owensby, C. Alisha, Knaus, Brian J., Elser, Justin, Miller, Daniel, Di, Yanming, McPhail, Kerry L., and Spatafora, Joseph W.
Abstract:: The ascomycete fungus Tolypocladium inflatum, a pathogen of beetle larvae, is best known as the producer of the immunosuppressant drug cyclosporin. The draft genome of T. inflatum strain NRRL 8044 (ATCC 34921), the isolate from which cyclosporin was first isolated, is presented along with comparative analyses of the biosynthesis of...
Resource Type:: Article
Full Text:: : Evolution, Organization, and Expression of the Cyclosporin Biosynthetic Gene Cluster Kathryn E. Bushley1

Mutualistic Co-evolution of Type III Effector Genes in Sinorhizobium fredii and Bradyrhizobium japonicum

Creator:: Kimbrel, Jeffrey A., Thomas, William J., Jiang, Yuan, Creason, Allison L., Thireault, Caitlin A., Sachs, Joel L., and Chang, Jeff H.
Abstract:: Two diametric paradigms have been proposed to model the molecular co-evolution of microbial mutualists and their eukaryotic hosts. In one, mutualist and host exhibit an antagonistic arms race and each partner evolves rapidly to maximize their own fitness from the interaction at potential expense of the other. In the opposing...
Resource Type:: Article
Full Text:: molecular co-evolution of microbial mutualists and their eukaryotic hosts. In one, mutualist and host

Simulated Evolution of Protein-Protein Interaction Networks with Realistic Topology

Creator:: Peterson, G. Jack, Pressé, Steve, Peterson, Kristin S., and Dill, Ken A.
Abstract:: We model the evolution of eukaryotic protein-protein interaction (PPI) networks. In our model, PPI networks evolve by two known biological mechanisms: (1) Gene duplication, which is followed by rapid diversification of duplicate interactions. (2) Neofunctionalization, in which a mutation leads to a new interaction with some other protein. Since many...
Resource Type:: Article
Full Text:: accompanies cellular evolution, and may be important for processes such as the emergence of antibiotic

Comparative Composition, Diversity and Trophic Ecology of Sediment Macrofauna at Vents, Seeps and Organic Falls

Creator:: Bernardino, Angelo F., Levin, Lisa A., Thurber, Andrew R., and Smith, Craig R.
Abstract:: Sediments associated with hydrothermal venting, methane seepage and large organic falls such as whale, wood and plant detritus create deep-sea networks of soft-sediment habitats fueled, at least in part, by the oxidation of reduced chemicals. Biological studies at deep-sea vents, seeps and organic falls have looked at macrofaunal taxa, but...
Resource Type:: Article
Full Text:: and Trophic Ecology of Sediment Macrofauna at Vents, Seeps and Organic Falls Angelo F. Bernardino1

The Genome and Development-Dependent Transcriptomes of Pyronema confluens: A Window into Fungal Evolution

Creator:: Traeger, Stefanie, Altegoer, Florian, Freitag, Michael, Gabaldon, Toni, Kempken, Frank, Kumar, Abhishek, Marcet-Houben, Marina, Poggeler, Stefanie, Stajich, Jason E., and Nowrousian, Minou
Abstract:: Fungi are a large group of eukaryotes found in nearly all ecosystems. More than 250 fungal genomes have already been sequenced, greatly improving our understanding of fungal evolution, physiology, and development. However, for the Pezizomycetes, an early-diverging lineage of filamentous ascomycetes, there is so far only one genome available, namely...
Resource Type:: Article
Full Text:: among basal filamentous ascomycetes, and to allow conclusions about the evolution of fungal development

Selfish Little Circles: Transmission Bias and Evolution of Large Deletion-Bearing Mitochondrial DNA in Caenorhabditis briggsae Nematodes

Creator:: Clark, Katie A., Howe, Dana K., Gafner, Kristin, Kusuma, Danika, Ping, Sita, Estes, Suzanne, and Denver, Dee R.
Abstract:: Selfish DNA poses a significant challenge to genome stability and organismal fitness in diverse eukaryotic lineages. Although selfish mitochondrial DNA (mtDNA) has known associations with cytoplasmic male sterility in numerous gynodioecious plant species and is manifested as petite mutants in experimental yeast lab populations, examples of selfish mtDNA in animals...
Resource Type:: Article
Full Text:: common. We analyzed the inheritance and evolution of mitochondrial DNA bearing large heteroplasmic

Using assessment of NSF data management plans to enable evidence-based evolution of research data services

Creator:: Whitmire, Amanda L., Carlson, Jake, Hswe, Patricia, Wells Parham, Susan, Rolando, Lizzy, and Westra, Brian
Abstract:: Funding agencies increasingly require a data management plan (DMP) with funding proposals, which describe how data generated in the proposed work will be managed, preserved and shared. Data management plans are a rich source of information about an institution’s researchers and their research data management (RDM) knowledge, capabilities, and needs....
Resource Type:: Presentation
Full Text:: a natural evolution of scope for us, and as we discussed yesterday, really isn’t so different than

Evolution of a Higher Intracellular Oxidizing Environment in Caenorhabditis elegans under Relaxed Selection

Creator:: Joyner-Matos, Joanna, Hicks, Kiley A., Cousins, Dustin, Keller, Michelle, Denver, Dee R., Baer, Charles F., and Estes, Suzanne
Abstract:: We explored the relationship between relaxed selection, oxidative stress, and spontaneous mutation in a set of mutation-accumulation (MA) lines of the nematode Caenorhabditis elegans and in their common ancestor. We measured steady-state levels of free radicals and oxidatively damaged guanosine nucleosides in the somatic tissues of five MA lines for...
Resource Type:: Article
Full Text:: evolution [23,24], the connection between variability in oxidative damage and variability in heritable

Patterns of loggerhead turtle ontogenetic shifts revealed through isotopic analysis of annual skeletal growth increments

Creator:: Ramirez, Matthew D., Avens, Larisa, Seminoff, Jeffrey A., Goshe, Lisa R., and Heppell, Selina S.
Abstract:: Ontogenetic changes in resource use often delimit transitions between life stages. Ecological and individual factors can cause variation in the timing and consistency of these transitions, ultimately affecting community and population dynamics through changes in growth and survival. Therefore, it is important to document and understand behavioral and life history...
Resource Type:: Article
Full Text:: ontogenetic changes in foraging ecology and habitat use in long-lived, cryptic marine species. Key words

In Vivo Quantification Reveals Extensive Natural Variation in Mitochondrial Form and Function in Caenorhabditis briggsae

Creator:: Hicks, Kiley A., Howe, Dana K., Leung, Aubrey, Denver, Dee R., and Estes, Suzanne
Abstract:: In We have analyzed natural variation in mitochondrial form and function among a set of Caenorhabditis briggsae isolates known to harbor mitochondrial DNA structural variation in the form of a heteroplasmic nad5 gene deletion (nad5 Delta) that correlates negatively with organismal fitness. We performed in vivo quantification of 24 mitochondrial...
Resource Type:: Article
Full Text:: -dependent mitochondrial traits has been implicated in the evolution and diversification of life-history

ScholarsArchive@OSU

The Genome of Tolypocladium inflatum: Evolution, Organization, and Expression of the Cyclosporin Biosynthetic Gene Cluster

Mutualistic Co-evolution of Type III Effector Genes in Sinorhizobium fredii and Bradyrhizobium japonicum

Simulated Evolution of Protein-Protein Interaction Networks with Realistic Topology

Comparative Composition, Diversity and Trophic Ecology of Sediment Macrofauna at Vents, Seeps and Organic Falls

The Genome and Development-Dependent Transcriptomes of Pyronema confluens: A Window into Fungal Evolution

Selfish Little Circles: Transmission Bias and Evolution of Large Deletion-Bearing Mitochondrial DNA in Caenorhabditis briggsae Nematodes

Using assessment of NSF data management plans to enable evidence-based evolution of research data services

Evolution of a Higher Intracellular Oxidizing Environment in Caenorhabditis elegans under Relaxed Selection

Patterns of loggerhead turtle ontogenetic shifts revealed through isotopic analysis of annual skeletal growth increments

In Vivo Quantification Reveals Extensive Natural Variation in Mitochondrial Form and Function in Caenorhabditis briggsae

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