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Filtering by: Creator Breen, Patrick J. License Attribution 3.0 United States

The ERI-6/7 Helicase Acts at the First Stage of an siRNA Amplification Pathway That Targets Recent Gene Duplications

Creator:

Fischer, Sylvia E. J., Montgomery, Taiowa A., Zhang, Chi, Fahlgren, Noah, Breen, Peter C., Hwang, Alexia, Sullivan, Christopher M., Carrington, James C., and Ruvkun, Gary

Abstract:

Endogenous small interfering RNAs (siRNAs) are a class of naturally occuring regulatory RNAs found in fungi, plants, and animals. Some endogenous siRNAs are required to silence transposons or function in chromosome segregation; however, the specific roles of most endogenous siRNAs are unclear. The helicase gene eri-6/7 was identified in the...

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of an siRNA Amplification Pathway That Targets Recent Gene Duplications Sylvia E. J. Fischer1, Taiowa
Lymphocytic Choriomeningitis Virus Infection in FVB Mouse Produces Hemorrhagic Disease

Creator:

Schnell, Frederick J., Sundholm, Sarah, Crumley, Stacy, Iversen, Patrick L., and Mourich, Dan V.

Abstract:

The viral family Arenaviridae includes a number of viruses that can cause hemorrhagic fever in humans. Arenavirus infection often involves multiple organs and can lead to capillary instability, impaired hemostasis, and death. Preclinical testing for development of antiviral or therapeutics is in part hampered due to a lack of an...

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Article

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in FVB Mouse Produces Hemorrhagic Disease Frederick J. Schnell1, Sarah Sundholm1, Stacy Crumley1