Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Creator Busboom, Jan Roger License Attribution 3.0 United States

Roles of brca2 (fancd1) in Oocyte Nuclear Architecture, Gametogenesis, Gonad Tumors, and Genome Stability in Zebrafish

Creator:

Rodriguez-Mari, Adriana, Wilson, Catherine, Titus, Tom A., Canestro, Cristian, BreMiller, Ruth A., Yan, Yi-Lin, Nanda, Indrajit, Johnston, Adam, Kanki, John P., Gray, Erin M., He, Xinjun, Spitsbergen, Jan, Schindler, Detlev, and Postlethwait, John H.

Abstract:

Mild mutations in BRCA2 (FANCD1) cause Fanconi anemia (FA) when homozygous, while severe mutations cause common cancers including breast, ovarian, and prostate cancers when heterozygous. Here we report a zebrafish brca2 insertional mutant that shares phenotypes with human patients and identifies a novel brca2 function in oogenesis. Experiments showed that...

Resource Type:

Article

Full Text:

, Adam Johnston3, John P. Kanki3, Erin M. Gray1, Xinjun He1, Jan Spitsbergen4, Detlev Schindler2, John H
Using Community Gardens To Help Solve the Hunger Crisis in San Diego County, CA

Creator:

Dusek, Daniel

Abstract:

The World Health Organization defines food security as “all people at all times have access to sufficient, safe, nutritious food to maintain a healthy and active life.” The reality is that one in six Americans are not food secure, even though the US produces enough food to feed its national...

Resource Type:

Capstone Project