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Filtering by: Creator Fleeger, John P. License Attribution 3.0 United States

What the Inbred Scandinavian Wolf Population Tells Us about the Nature of Conservation

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Räikkönen, Jannikke, Vucetich, John A., Vucetich, Leah M., Peterson, Rolf O., and Nelson, Michael P.

Abstract:

The genetic aspects of population health are critical, but frequently difficult to assess. Of concern has been the genetic constitution of Scandinavian wolves (Canis lupus), which represent an important case in conservation. We examined the incidence of different congenital anomalies for 171 Scandinavian wolves, including the immigrant founder female, born...

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Tells Us about the Nature of Conservation Jannikke Räikkönen1*, John A. Vucetich2, Leah M. Vucetich2
Roles of brca2 (fancd1) in Oocyte Nuclear Architecture, Gametogenesis, Gonad Tumors, and Genome Stability in Zebrafish

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Rodriguez-Mari, Adriana, Wilson, Catherine, Titus, Tom A., Canestro, Cristian, BreMiller, Ruth A., Yan, Yi-Lin, Nanda, Indrajit, Johnston, Adam, Kanki, John P., Gray, Erin M., He, Xinjun, Spitsbergen, Jan, Schindler, Detlev, and Postlethwait, John H.

Abstract:

Mild mutations in BRCA2 (FANCD1) cause Fanconi anemia (FA) when homozygous, while severe mutations cause common cancers including breast, ovarian, and prostate cancers when heterozygous. Here we report a zebrafish brca2 insertional mutant that shares phenotypes with human patients and identifies a novel brca2 function in oogenesis. Experiments showed that...

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, Adam Johnston3, John P. Kanki3, Erin M. Gray1, Xinjun He1, Jan Spitsbergen4, Detlev Schindler2, John H

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What the Inbred Scandinavian Wolf Population Tells Us about the Nature of Conservation

Roles of brca2 (fancd1) in Oocyte Nuclear Architecture, Gametogenesis, Gonad Tumors, and Genome Stability in Zebrafish

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