Index Catalog // ScholarsArchive@OSU

A genome scale metabolic network for rice and accompanying analysis of tryptophan, auxin and serotonin biosynthesis regulation under biotic stress

Creator:: Dharmawardhana, Palitha, Ren, Liya, Amarasinghe, Vindhya, Monaco, Marcela, Thomason, Jim, Ravenscroft, Dean, McCouch, Susan, Ware, Doreen, and Jaiswal, Pankaj
Abstract:: Background: Functional annotations of large plant genome projects mostly provide information on gene function and gene families based on the presence of protein domains and gene homology, but not necessarily in association with gene expression or metabolic and regulatory networks. These additional annotations are necessary to understand the physiology, development...
Resource Type:: Article
Full Text:: families based on the presence of protein domains and gene homology, but not necessarily in association

Circadian Regulation of Glutathione Levels and Biosynthesis in Drosophila melanogaster

Creator:: Beaver, Laura M., Klichko, Vladimir I., Chow, Eileen S., Kotwica-Rolinska, Joanna, Williamson, Marisa, Orr, William C., Radyuk, Svetlana N., and Giebultowicz, Jadwiga M.
Abstract:: Circadian clocks generate daily rhythms in neuronal, physiological, and metabolic functions. Previous studies in mammals reported daily fluctuations in levels of the major endogenous antioxidant, glutathione (GSH), but the molecular mechanisms that govern such fluctuations remained unknown. To address this question, we used the model species Drosophila, which has a...
Resource Type:: Article
Full Text:: and Biosynthesis in Drosophila melanogaster Laura M. Beaver1¤a, Vladimir I. Klichko2, Eileen S. Chow1

Nested scales of spatial heterogeneity in juvenile walleye pollock Theragra chalcogramma in the southeastern Bering Sea

Creator:: Benoit-Bird, Kelly J., McIntosh, Neal E., and Heppell, Scott A.
Abstract:: We sought to characterize the distribution of juvenile walleye pollock Theragra chalcogramma in an area of intense predator-prey interactions and to describe habitat features that lead to their observed distributions. The distribution of juvenile walleye pollock around the Pribilof Islands in the southeastern Bering Sea in 2008 and 2009 was...
Resource Type:: Article
Full Text:: phenom- enon in the ocean (Steele 1978). Significant spatial variations in oceanic biomass, e.g. patches

Estimating heterotrophic respiration at large scales: challenges, approaches, and next steps

Creator:: Bond-Lamberty, Ben, Epron, Daniel, Harden, Jennifer, Harmon, Mark E., Hoffman, Forrest, Kumar, Jitendra, David McGuire, Anthony, and Vargas, Rodrigo
Abstract:: Heterotrophic respiration (HR), the aerobic and anaerobic processes mineralizing organic matter, is a key carbon flux but one impossible to measure at scales significantly larger than small experimental plots. This impedes our ability to understand carbon and nutrient cycles, benchmark models, or reliably upscale point measurements. Given that a new...
Resource Type:: Article
Full Text:: types (PFTs), DFTs would abstract and capture important differences in HR metabolism and flux dynamics

Lymphocytic Choriomeningitis Virus Infection in FVB Mouse Produces Hemorrhagic Disease

Creator:: Schnell, Frederick J., Sundholm, Sarah, Crumley, Stacy, Iversen, Patrick L., and Mourich, Dan V.
Abstract:: The viral family Arenaviridae includes a number of viruses that can cause hemorrhagic fever in humans. Arenavirus infection often involves multiple organs and can lead to capillary instability, impaired hemostasis, and death. Preclinical testing for development of antiviral or therapeutics is in part hampered due to a lack of an...
Resource Type:: Article
Full Text:: in FVB Mouse Produces Hemorrhagic Disease Frederick J. Schnell1, Sarah Sundholm1, Stacy Crumley1

Differential surface activation of the A1 domain of von Willebrand factor

Creator:: Tronic, Elaine H., Yakovenko, Olga, Weidner, Tobias, Baio, Joe E., Penkala, Rebecca, Castner, David G., and Thomas, Wendy E.
Abstract:: The clotting protein von Willebrand factor (VWF) binds to platelet receptor glycoprotein Ibα (GPIbα) when VWF is activated by chemicals, high shear stress, or immobilization onto surfaces. Activation of VWF by surface immobilization is an important problem in the failure of cardiovascular implants, but is poorly understood. Here, the authors...
Resource Type:: Article
Full Text:: onto surfaces. Activation of VWF by surface immobilization is an important problem in the failure of

Coibamide A Induces mTOR-Independent Autophagy and Cell Death in Human Glioblastoma Cells

Creator:: Hau, Andrew M., Greenwood, Jeffrey A., Lohr, Christiane V., Serrill, Jeffrey D., Proteau, Philip J., Ganley, Ian G., McPhail, Kerry L., and Ishmael, Jane E.
Abstract:: Coibamide A is an N-methyl-stabilized depsipeptide that was isolated from a marine cyanobacterium as part of an International Cooperative Biodiversity Groups (ICBG) program based in Panama. Previous testing of coibamide A in the NCI in vitro 60 cancer cell line panel revealed a potent anti-proliferative response and "COMPARE-negative" profile indicative...
Resource Type:: Article
Full Text:: Autophagy and Cell Death in Human Glioblastoma Cells Andrew M. Hau1, Jeffrey A. Greenwood2, Christiane V

Where to find 1.5 million yr old ice for the IPICS “Oldest-Ice” ice core

Creator:: Fischer, H., Severinghaus, J., Brook, Edward J., Wolff, E., Albert, M., Alemany, O., Arthern, R., Bentley, C., Blankenship, D., Chappellaz, J., Creyts, T., Dahl-Jensen, D., Dinn, M., Frezzotti, M., Fujita, S., Gallee, H., Hindmarsh, R., Hudspeth, D., Jugie, G., Kawamura, K., Lipenkov, V., Miller, H., Mulvaney, R., Parrenin, F., Pattyn, F., Ritz, C., Schwander, J., Steinhage, D., van Ommen, T., and Wilhelms, F.
Abstract:: The recovery of a 1.5 million yr long ice core from Antarctica represents a keystone of our understanding of Quaternary climate, the progression of glaciation over this time period and the role of greenhouse gas cycles in this progression. Here we tackle the question of where such ice may still...
Resource Type:: Article
Full Text:: .) Received: 30 April 2013 – Published in Clim. Past Discuss.: 27 May 2013 Revised: 19 September 2013

High-Density SNP Genotyping of Tomato (Solanum lycopersicum L.) Reveals Patterns of Genetic Variation Due to Breeding

Creator:: Sim, Sung-Chur, Van Deynze, Allen, Stoffel, Kevin, Douches, David S., Zarka, Daniel, Ganal, Martin W., Chetelat, Roger T., Hutton, Samuel F., Scott, John W., Gardner, Randolph G., Panthee, Dilip R., Mutschler, Martha, Myers, James R., and Francis, David M.
Abstract:: The effects of selection on genome variation were investigated and visualized in tomato using a high-density single nucleotide polymorphism (SNP) array. 7,720 SNPs were genotyped on a collection of 426 tomato accessions (410 inbreds and 16 hybrids) and over 97% of the markers were polymorphic in the entire collection. Principal...
Resource Type:: Article
Full Text:: investigated and visualized in tomato using a high-density single nucleotide polymorphism (SNP) array. 7,720

High-Throughput Sequencing of Arabidopsis microRNAs : Evidence for Frequent Birth and Death of MIRNA Genes

Creator:: Fahlgren, Noah, Howell, Miya D., Kasschau, Kristin D., Sullivan, Christopher M., Cumbie, Jason S., Givan, Scott A., Law, Theresa F., Grant, Sarah R., Dangl, Jeffrey L., and Carrington, James C.
Abstract:: In plants, microRNAs (miRNAs) comprise one of two classes of small RNAs that function primarily as negative regulators at the posttranscriptional level. Several MIRNA genes in the plant kingdom are ancient, with conservation extending between angiosperms and the mosses, whereas many others are more recently evolved. Here, we use deep...
Resource Type:: Article
Full Text:: , North Carolina, United States of America In plants, microRNAs (miRNAs) comprise one of two classes of

ScholarsArchive@OSU

A genome scale metabolic network for rice and accompanying analysis of tryptophan, auxin and serotonin biosynthesis regulation under biotic stress

Circadian Regulation of Glutathione Levels and Biosynthesis in Drosophila melanogaster

Nested scales of spatial heterogeneity in juvenile walleye pollock Theragra chalcogramma in the southeastern Bering Sea

Estimating heterotrophic respiration at large scales: challenges, approaches, and next steps

Lymphocytic Choriomeningitis Virus Infection in FVB Mouse Produces Hemorrhagic Disease

Differential surface activation of the A1 domain of von Willebrand factor

Coibamide A Induces mTOR-Independent Autophagy and Cell Death in Human Glioblastoma Cells

Where to find 1.5 million yr old ice for the IPICS “Oldest-Ice” ice core

High-Density SNP Genotyping of Tomato (Solanum lycopersicum L.) Reveals Patterns of Genetic Variation Due to Breeding

High-Throughput Sequencing of Arabidopsis microRNAs : Evidence for Frequent Birth and Death of MIRNA Genes

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