Index Catalog // ScholarsArchive@OSU

3,3'-Diindolylmethane Induces G₁ Arrest and Apoptosis in Human Acute T-Cell Lymphoblastic Leukemia Cells

Creator:: Shorey, Lyndsey E., Hagman, Amanda M., Williams, David E., Ho, Emily, Dashwood, Roderick H., and Benninghoff, Abby D.
Abstract:: Certain bioactive food components, including indole-3-carbinol (I3C) and 3,3'-diindolylmethane (DIM) from cruciferous vegetables, have been shown to target cellular pathways regulating carcinogenesis. Previously, our laboratory showed that dietary I3C is an effective transplacental chemopreventive agent in a dibenzo[def,p]chrysene (DBC)-dependent model of murine T-cell lymphoblastic lymphoma. The primary objective of the...
Resource Type:: Article
Full Text:: Environmental and Molecular Toxicology, Oregon State University, Corvallis, Oregon, United States of America, 2

Delayed Cutaneous Wound Healing and Aberrant Expression of Hair Follicle Stem Cell Markers in Mice Selectively Lacking Ctip2 in Epidermis

Creator:: Liang, Xiaobo, Bhattacharya, Shreya, Bajaj, Gaurav, Guha, Gunjan, Wang, Zhixing, Jang, Hyo-Sang, Leid, Mark, Indra, Arup Kumar, and Ganguli-Indra, Gitali
Abstract:: Background: COUP-TF interacting protein 2 [(Ctip2), also known as Bcl11b] is an important regulator of skin homeostasis, and is overexpressed in head and neck cancer. Ctip2(ep-/-) mice, selectively ablated for Ctip2 in epidermal keratinocytes, exhibited impaired terminal differentiation and delayed epidermal permeability barrier (EPB) establishment during development, similar to what...
Resource Type:: Article
Full Text:: Pharmacy, Oregon State University, Corvallis, United States of America, 2 Molecular and Cell Biology

Comparison of fixatives and fixation time for PCR detection of Mycobacterium in zebrafish Danio rerio

Creator:: Peterson, Tracy S., Kent, Michael L., Ferguson, Jayde A., Watral, Virginia G., and Whipps, Christopher M.
Abstract:: Mycobacteriosis is a common disease of laboratory zebrafish Danio rerio. Different infection patterns occur in zebrafish depending on mycobacterial species. Mycobacterium marinum and M. haemophilum produce virulent infections associated with high mortality, whereas M. chelonae is more widespread and is not associated with high mortality. Identification of mycobacterial infections to...
Resource Type:: Article
Full Text:: denaturation and coagulation of proteins and nucleic acids within tis- sue specimens by dehydration and

Mutualistic Co-evolution of Type III Effector Genes in Sinorhizobium fredii and Bradyrhizobium japonicum

Creator:: Kimbrel, Jeffrey A., Thomas, William J., Jiang, Yuan, Creason, Allison L., Thireault, Caitlin A., Sachs, Joel L., and Chang, Jeff H.
Abstract:: Two diametric paradigms have been proposed to model the molecular co-evolution of microbial mutualists and their eukaryotic hosts. In one, mutualist and host exhibit an antagonistic arms race and each partner evolves rapidly to maximize their own fitness from the interaction at potential expense of the other. In the opposing...
Resource Type:: Article
Full Text:: America, 2 Molecular and Cellular Biology Program, Oregon State University, Corvallis, Oregon, United

Frequent Alteration of the Tumor Suppressor Gene APC in Sporadic Canine Colorectal Tumors

Creator:: Youmans, Lydia, Taylor, Cynthia, Shin, Edwin, Harrell, Adrienne, Ellis, Angela E., Seguin, Bernard, Ji, Xinglai, and Zhao, Shaying
Abstract:: Sporadic canine colorectal cancers (CRCs) should make excellent models for studying the corresponding human cancers. To molecularly characterize canine CRC, we investigated exonic sequence mutations of adenomatous polyposis coli (APC), the best known tumor suppressor gene of human CRC, in 23 sporadic canine colorectal tumors, including 8 adenomas and 15...
Resource Type:: Article
Full Text:: somatic mutations in human tumors and cell lines. Nucleic Acids Res 26: 269– 270. 33. Miyaki M, Iijima T

Mechanistic Insights into Validoxylamine A 7’-Phosphate Synthesis by VldE Using the Structure of the Entire Product Complex

Creator:: Cavalier, Michael C., Yim, Young-Sun, Asamizu, Shumpei, Neau, David, Almabruk, Khaled H., Mahmud, Taifo, and Lee, Yong-Hwan
Abstract:: The pseudo-glycosyltransferase VldE catalyzes non-glycosidic C-N coupling between an unsaturated cyclitol and a saturated aminocyclitol with the conservation of the stereochemical configuration of the substrates to form validoxylamine A 7'-phosphate, the biosynthetic precursor of the antibiotic validamycin A. To study the molecular basis of its mechanism, the three-dimensional structures of...
Resource Type:: Article
Full Text:: . To study the molecular basis of its mechanism, the three-dimensional structures of VldE from

Phylogeny of minute carabid beetles and their relatives based upon DNA sequence data (Coleoptera, Carabidae, Trechitae)

Creator:: Maddison, David R. and Ober, Karen A.
Abstract:: The phylogeny of ground beetles of supertribe Trechitae is inferred using DNA sequences of genes that code for 28S ribosomal RNA, 18S ribosomal RNA, and wingless. Within the outgroups, austral psydrines are inferred to be monophyletic, and separate from the three genera of true Psydrina (Psydrus, Nomius, Laccocenus); the austral...
Resource Type:: Article
Full Text:: Keywords ground beetles, DNA, molecular phylogeny, Bembidiini, Trechinae, Carabidae, Trechitae

WikiPathways for plants: a community pathway curation portal and a case study in rice and arabidopsis seed development networks

Creator:: Hanumappa, Mamatha, Preece, Justin, Elser, Justin, Nemeth, Denise, Bono, Gina, Wu, Kenny, and Jaiswal, Pankaj
Abstract:: Background: Next-generation sequencing and 'omics' platforms are used extensively in plant biology research to unravel new genomes and study their interactions with abiotic and biotic agents in the growth environment. Despite the availability of a large and growing number of genomic data sets, there are only limited resources providing highly-curated...
Resource Type:: Article
Full Text:: database. Nucleic Acids Res 31(1):248–250 Caspi R, Altman T et al (2012) The MetaCyc database of metabolic

The Genome of Tolypocladium inflatum: Evolution, Organization, and Expression of the Cyclosporin Biosynthetic Gene Cluster

Creator:: Bushley, Kathryn E., Raja, Rajani, Jaiswal, Pankaj, Cumbie, Jason S., Nonogaki, Mariko, Boyd, Alexander E., Owensby, C. Alisha, Knaus, Brian J., Elser, Justin, Miller, Daniel, Di, Yanming, McPhail, Kerry L., and Spatafora, Joseph W.
Abstract:: The ascomycete fungus Tolypocladium inflatum, a pathogen of beetle larvae, is best known as the producer of the immunosuppressant drug cyclosporin. The draft genome of T. inflatum strain NRRL 8044 (ATCC 34921), the isolate from which cyclosporin was first isolated, is presented along with comparative analyses of the biosynthesis of...
Resource Type:: Article
Full Text:: with GO molecular functions of protein binding (22–26% vs 13–16%), oxidoreductase activity (20% vs 8

Complete genome sequence of Nitrosomonas sp. Is79, an ammonia oxidizing bacterium adapted to low ammonium concentrations

Creator:: Bollmann, Annette, Sedlacek, Christopher J., Norton, Jeanette, Laanbroek, Hendrikus J., Suwa, Yuichi, Stein, Lisa Y., Klotz, Martin G., Arp, Daniel J., Sayavedra-Soto, Luis, Lu, Megan, Bruce, David, Detter, Chris, Tapia, Roxanne, Han, James, Woyke, Tanja, Pitluck, Sam, Pennacchio, Len, Nolan, Matt, Land, Miriam L., Huntemann, Marcel, Deshpande, Shweta, Han, Cliff, Chen, Amy, Kyrpides, Nikos, Movromatis, Konstantinos, Markowitz, Victor, Szeto, Ernest, Ivonova, Natalia, Mikhailova, Natalia, Pagani, Ioanna, Pati, Amrita, Peters, Lin, Ovchinnikova, Galina, Goodwin, Lynne A., and Lucas, Susan M.
Abstract:: Nitrosomonas sp. Is79 is a chemolithoautotrophic ammonia-oxidizing bacterium that belongs to the family Nitrosomonadaceae within the phylum Proteobacteria. Ammonia oxidation is the first step of nitrification, an important process in the global nitrogen cycle ultimately resulting in the production of nitrate. Nitrosomonas sp. Is79 is an ammonia oxidizer of high...
Resource Type:: Article
Full Text:: detection of transfer RNA genes in ge- nomic sequence. Nucleic Acids Res 1997; 25:955-964. PubMed 51

ScholarsArchive@OSU

3,3'-Diindolylmethane Induces G₁ Arrest and Apoptosis in Human Acute T-Cell Lymphoblastic Leukemia Cells

Delayed Cutaneous Wound Healing and Aberrant Expression of Hair Follicle Stem Cell Markers in Mice Selectively Lacking Ctip2 in Epidermis

Comparison of fixatives and fixation time for PCR detection of Mycobacterium in zebrafish Danio rerio

Mutualistic Co-evolution of Type III Effector Genes in Sinorhizobium fredii and Bradyrhizobium japonicum

Frequent Alteration of the Tumor Suppressor Gene APC in Sporadic Canine Colorectal Tumors

Mechanistic Insights into Validoxylamine A 7’-Phosphate Synthesis by VldE Using the Structure of the Entire Product Complex

Phylogeny of minute carabid beetles and their relatives based upon DNA sequence data (Coleoptera, Carabidae, Trechitae)

WikiPathways for plants: a community pathway curation portal and a case study in rice and arabidopsis seed development networks

The Genome of Tolypocladium inflatum: Evolution, Organization, and Expression of the Cyclosporin Biosynthetic Gene Cluster

Complete genome sequence of Nitrosomonas sp. Is79, an ammonia oxidizing bacterium adapted to low ammonium concentrations

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