Index Catalog // ScholarsArchive@OSU

Differential surface activation of the A1 domain of von Willebrand factor

Creator:: Tronic, Elaine H., Yakovenko, Olga, Weidner, Tobias, Baio, Joe E., Penkala, Rebecca, Castner, David G., and Thomas, Wendy E.
Abstract:: The clotting protein von Willebrand factor (VWF) binds to platelet receptor glycoprotein Ibα (GPIbα) when VWF is activated by chemicals, high shear stress, or immobilization onto surfaces. Activation of VWF by surface immobilization is an important problem in the failure of cardiovascular implants, but is poorly understood. Here, the authors...
Resource Type:: Article
Full Text:: Willebrand factor Elaine H. Tronic, Olga Yakovenko, and Tobias Weidnera) Department of Bioengineering

Roles of brca2 (fancd1) in Oocyte Nuclear Architecture, Gametogenesis, Gonad Tumors, and Genome Stability in Zebrafish

Creator:: Rodriguez-Mari, Adriana, Wilson, Catherine, Titus, Tom A., Canestro, Cristian, BreMiller, Ruth A., Yan, Yi-Lin, Nanda, Indrajit, Johnston, Adam, Kanki, John P., Gray, Erin M., He, Xinjun, Spitsbergen, Jan, Schindler, Detlev, and Postlethwait, John H.
Abstract:: Mild mutations in BRCA2 (FANCD1) cause Fanconi anemia (FA) when homozygous, while severe mutations cause common cancers including breast, ovarian, and prostate cancers when heterozygous. Here we report a zebrafish brca2 insertional mutant that shares phenotypes with human patients and identifies a novel brca2 function in oogenesis. Experiments showed that...
Resource Type:: Article
Full Text:: , Adam Johnston3, John P. Kanki3, Erin M. Gray1, Xinjun He1, Jan Spitsbergen4, Detlev Schindler2, John H

The VAMOS Ocean-Cloud-Atmosphere-Land Study Regional Experiment (VOCALS-REx): goals, platforms, and field operations

Creator:: Wood, R., Mechoso, C. R., Bretherton, C. S., Weller, R. A., Huebert, B., Straneo, F., Albrecht, B. A., Coe, H., Allen, G., Vaughan, G., Daum, P., Fairall, C., Chand, D., Klenner, L. Gallardo, Garreaud, R., Grados, C., Covert, D. S., Bates, T. S., Krejci, R., Russell, L. M., de Szoeke, Simon P., Brewer, A., Yuter, S. E., Springston, S. R., Chaigneau, A., Toniazzo, T., Minnis, P., Palikonda, R., Abel, S. J., Brown, W. O. J., Williams, S., Fochesatto, J., Brioude, J., and Bower, K. N.
Abstract:: The VAMOS Ocean-Cloud-Atmosphere-Land Study Regional Experiment (VOCALS-REx) was an international field program designed to make observations of poorly understood but critical components of the coupled climate system of the southeast Pacific. This region is characterized by strong coastal upwelling, the coolest SSTs in the tropical belt, and is home to...
Resource Type:: Article
Full Text:: . Straneo3, B. A. Albrecht5, H. Coe6, G. Allen6, G. Vaughan6, P. Daum7, C. Fairall8, D. Chand1,*, L. Gallardo

Catalyst selective and regiodivergent O- to C- or N-carboxyl transfer of pyrazolyl carbonates: synthetic and computational studies

Creator:: Gould, Eoin, Walden, Daniel M., Kasten, Kevin, Johnston, Ryne C., Wu, Jiufeng, Slawin, Alexandra M., Mustard, Thomas J. L., Johnston, Brittany, Davies, Tony, Cheong, Paul Ha-Yeon, and Smith, Andrew D.
Abstract:: The regiodivergent O- to C- or N-carboxyl transfer of pyrazolyl carbonates is described, with DMAP giving preferential N-carboxylation and triazolinylidenes promoting selective C-carboxylation (both with up to >99 : 1 regioselectivity). An enantioselective O- to C-carboxyl variant using NHC catalysis is demonstrated (up to 92% ee), while mechanistic and DFT studies outline...
Resource Type:: Article
Full Text:: . 3 S. A. Shaw, P. Aleman and E. Vedejs, J. Am. Chem. Soc., 2003, 125, 13368–13369. 4 H. V. Nguyen, D

Endosperm Tolerance of Paternal Aneuploidy Allows Radiation Hybrid Mapping of the Wheat D-Genome and a Measure of γ Ray-Induced Chromosome Breaks

Creator:: Tiwari, Vijay K., Riera-Lizarazu, Oscar, Gunn, Hilary L., Lopez, KaSandra, Iqbal, M. Javed, Kianian, Shahryar F., and Leonard, Jeffrey M.
Abstract:: Physical mapping and genome sequencing are underway for the ≈17 Gb wheat genome. Physical mapping methods independent of meiotic recombination, such as radiation hybrid (RH) mapping, will aid precise anchoring of BAC contigs in the large regions of suppressed recombination in Triticeae genomes. Reports of endosperm development following pollination with...
Resource Type:: Article

The plant phenology monitoring design for The National Ecological Observatory Network

Creator:: Elmendorf, Sarah C., Jones, Katherine D., Cook, Benjamin I., Diez, Jeffrey M., Enquist, Carolyn A. F., Hufft, Rebecca A., Jones, Matthew O., Mazer, Susan J., Miller-Rushing, Abraham J., Moore, David J. P., Schwartz, Mark D., and Weltzin, Jake F.
Abstract:: Phenology is an integrative science that comprises the study of recurring biological activities or events. In an era of rapidly changing climate, the relationship between the timing of those events and environmental cues such as temperature, snowmelt, water availability, or day length are of particular interest. This article provides an...
Resource Type:: Article
Full Text:: increased sample size (Nguyen et al. 2009). Phenophase status assessment using USA- NPN definitions shows

Frequent Alteration of the Tumor Suppressor Gene APC in Sporadic Canine Colorectal Tumors

Creator:: Youmans, Lydia, Taylor, Cynthia, Shin, Edwin, Harrell, Adrienne, Ellis, Angela E., Seguin, Bernard, Ji, Xinglai, and Zhao, Shaying
Abstract:: Sporadic canine colorectal cancers (CRCs) should make excellent models for studying the corresponding human cancers. To molecularly characterize canine CRC, we investigated exonic sequence mutations of adenomatous polyposis coli (APC), the best known tumor suppressor gene of human CRC, in 23 sporadic canine colorectal tumors, including 8 adenomas and 15...
Resource Type:: Article
Full Text:: -frozen sample cryosectioning, H&E staining, and cryo- microdissection were performed as described

Delayed Cutaneous Wound Healing and Aberrant Expression of Hair Follicle Stem Cell Markers in Mice Selectively Lacking Ctip2 in Epidermis

Creator:: Liang, Xiaobo, Bhattacharya, Shreya, Bajaj, Gaurav, Guha, Gunjan, Wang, Zhixing, Jang, Hyo-Sang, Leid, Mark, Indra, Arup Kumar, and Ganguli-Indra, Gitali
Abstract:: Background: COUP-TF interacting protein 2 [(Ctip2), also known as Bcl11b] is an important regulator of skin homeostasis, and is overexpressed in head and neck cancer. Ctip2(ep-/-) mice, selectively ablated for Ctip2 in epidermal keratinocytes, exhibited impaired terminal differentiation and delayed epidermal permeability barrier (EPB) establishment during development, similar to what...
Resource Type:: Article
Full Text:: dorsal side. 24 h later, the shaved skin was topically treated with 10 nmol TPA (Sigma: St.Louis, MO

High-Density SNP Genotyping of Tomato (Solanum lycopersicum L.) Reveals Patterns of Genetic Variation Due to Breeding

Creator:: Sim, Sung-Chur, Van Deynze, Allen, Stoffel, Kevin, Douches, David S., Zarka, Daniel, Ganal, Martin W., Chetelat, Roger T., Hutton, Samuel F., Scott, John W., Gardner, Randolph G., Panthee, Dilip R., Mutschler, Martha, Myers, James R., and Francis, David M.
Abstract:: The effects of selection on genome variation were investigated and visualized in tomato using a high-density single nucleotide polymorphism (SNP) array. 7,720 SNPs were genotyped on a collection of 426 tomato accessions (410 inbreds and 16 hybrids) and over 97% of the markers were polymorphic in the entire collection. Principal...
Resource Type:: Article
Full Text:: -populations, the curves reached an Table 2. Pairwise estimates of Fst (h) between sub-populations. Sub

ScholarsArchive@OSU

Differential surface activation of the A1 domain of von Willebrand factor

Roles of brca2 (fancd1) in Oocyte Nuclear Architecture, Gametogenesis, Gonad Tumors, and Genome Stability in Zebrafish

The VAMOS Ocean-Cloud-Atmosphere-Land Study Regional Experiment (VOCALS-REx): goals, platforms, and field operations

Catalyst selective and regiodivergent O- to C- or N-carboxyl transfer of pyrazolyl carbonates: synthetic and computational studies

Endosperm Tolerance of Paternal Aneuploidy Allows Radiation Hybrid Mapping of the Wheat D-Genome and a Measure of γ Ray-Induced Chromosome Breaks

The plant phenology monitoring design for The National Ecological Observatory Network

Frequent Alteration of the Tumor Suppressor Gene APC in Sporadic Canine Colorectal Tumors

Delayed Cutaneous Wound Healing and Aberrant Expression of Hair Follicle Stem Cell Markers in Mice Selectively Lacking Ctip2 in Epidermis

High-Density SNP Genotyping of Tomato (Solanum lycopersicum L.) Reveals Patterns of Genetic Variation Due to Breeding

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