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Filtering by: Creator O’Connor, Alison E. License Attribution 3.0 United States

Evaluating Paratransgenesis as a Potential Control Strategy for African Trypanosomiasis

Creator:

Medlock, Jan, Atkins, Katherine E., Thomas, David N., Aksoy, Serap, and Galvani, Alison P.

Abstract:

Genetic-modification strategies are currently being developed to reduce the transmission of vector-borne diseases, including African trypanosomiasis. For tsetse, the vector of African trypanosomiasis, a paratransgenic strategy is being considered: this approach involves modification of the commensal symbiotic bacteria Sodalis to express trypanosome-resistance-conferring products. Modified Sodalis can then be driven into...

Resource Type:

Article

Full Text:

Control Strategy for African Trypanosomiasis Jan Medlock1,2*, Katherine E. Atkins2, David N. Thomas2