Index Catalog // ScholarsArchive@OSU

Uncertainty analysis: an evaluation metric for synthesis science

Creator:: Harmon, Mark E., Fasth, Becky, Halpern, Charles B., and Lutz, James A.
Abstract:: The methods for conducting reductionist ecological science are well known and widely used. In contrast, those used in the synthesis of ecological science (i.e., synthesis science) are still being developed, vary widely, and often lack the rigor of reductionist approaches. This is unfortunate because the synthesis of ecological parts into...
Resource Type:: Article
Full Text:: ,1 CHARLES B. HALPERN,2 AND JAMES A. LUTZ3 1Department of Forest Ecosystems and Society, Oregon

Footprint of Positive Selection in Treponema pallidum subsp. pallidum Genome Sequences Suggests Adaptive Microevolution of the Syphilis Pathogen

Creator:: Giacani, Lorenzo, Chattopadhyay, Sujay, Centurion-Lara, Arturo, Jeffrey, BrendanM., Le, Hoavan T., Molini, Barbara J., Lukehart, Sheila A., Sokurenko, Evgeni V., and Rockey, Daniel D.
Abstract:: In the rabbit model of syphilis, infection phenotypes associated with the Nichols and Chicago strains of Treponema pallidum (T. pallidum), though similar, are not identical. Between these strains, significant differences are found in expression of, and antibody responses to some candidate virulence factors, suggesting the existence of functional genetic differences...
Resource Type:: Article
Full Text:: . Molini1, Sheila A. Lukehart1,4, Evgeni V. Sokurenko2, Daniel D. Rockey3 1 Department of Medicine

Coibamide A Induces mTOR-Independent Autophagy and Cell Death in Human Glioblastoma Cells

Creator:: Hau, Andrew M., Greenwood, Jeffrey A., Lohr, Christiane V., Serrill, Jeffrey D., Proteau, Philip J., Ganley, Ian G., McPhail, Kerry L., and Ishmael, Jane E.
Abstract:: Coibamide A is an N-methyl-stabilized depsipeptide that was isolated from a marine cyanobacterium as part of an International Cooperative Biodiversity Groups (ICBG) program based in Panama. Previous testing of coibamide A in the NCI in vitro 60 cancer cell line panel revealed a potent anti-proliferative response and "COMPARE-negative" profile indicative...
Resource Type:: Article
Full Text:: Autophagy and Cell Death in Human Glioblastoma Cells Andrew M. Hau1, Jeffrey A. Greenwood2, Christiane V

Intra‐ and inter‐annual variation in gray whale body condition on a foraging ground

Creator:: Soledade Lemos, Leila, Burnett, Jonathan D., Chandler, Todd E., Sumich, James L., and Torres, Leigh G.
Abstract:: Baleen whales store energy gained on foraging grounds to support reproduction and other metabolic needs while fasting for long periods during migration. Whale body condition can be used to monitor foraging success, and thus better understand and anticipate individual‐ and population‐level trends in reproduction and survival. We assessed the body...
Resource Type:: Article
Full Text:: foraging ground LEILA SOLEDADE LEMOS ,1,� JONATHAN D. BURNETT ,2 TODD E. CHANDLER,1 JAMES L. SUMICH ,3

Genome-Wide Profiling and Analysis of Arabidopsis siRNAs

Creator:: Kasschau, Kristin D., Fahlgren, Noah, Chapman, Elisabeth J., Sullivan, Christopher M., Cumbie, Jason S., Givan, Scott A., and Carrington, James C.
Abstract:: Eukaryotes contain a diversified set of small RNA-guided pathways that control genes, repeated sequences, and viruses at the transcriptional and posttranscriptional levels. Genome-wide profiles and analyses of small RNAs, particularly the large class of 24-nucleotide (nt) short interfering RNAs (siRNAs), were done for wild-type Arabidopsis thaliana and silencing pathway mutants...
Resource Type:: Article
Full Text:: . Sullivan 1,2 , Jason S. Cumbie 1,2 , Scott A. Givan 1,2 , James C. Carrington 1,2* 1 Center for Genome

Genetic and Functional Diversification of Small RNA Pathways in Plants

Creator:: Xie, Zhixin, Johansen, Lisa K., Gustafan, Adam M., Kasschau, Kristin D., Lellis, Andrew D., Zilberman, Daniel, Jacobsen, Steven E., and Carrington, James C.
Abstract:: Multicellular eukaryotes produce small RNA molecules (approximately 21–24 nucleotides) of two general types, microRNA (miRNA) and short interfering RNA (siRNA). They collectively function as sequence-specific guides to silence or regulate genes, transposons, and viruses and to modify chromatin and genome structure. Formation or activity of small RNAs requires factors belonging...
Resource Type:: Article
Full Text:: . Kasschau 1 , Andrew D. Lellis 1 , Daniel Zilberman 2 , Steven E. Jacobsen 2,3 , James C. Carrington 1

High-Throughput Sequencing of Arabidopsis microRNAs : Evidence for Frequent Birth and Death of MIRNA Genes

Creator:: Fahlgren, Noah, Howell, Miya D., Kasschau, Kristin D., Sullivan, Christopher M., Cumbie, Jason S., Givan, Scott A., Law, Theresa F., Grant, Sarah R., Dangl, Jeffrey L., and Carrington, James C.
Abstract:: In plants, microRNAs (miRNAs) comprise one of two classes of small RNAs that function primarily as negative regulators at the posttranscriptional level. Several MIRNA genes in the plant kingdom are ancient, with conservation extending between angiosperms and the mosses, whereas many others are more recently evolved. Here, we use deep...
Resource Type:: Article
Full Text:: . Law3, Sarah R. Grant3, Jeffery L. Dangl3, James C. Carrington1* 1 Center for Genome Research and

The ERI-6/7 Helicase Acts at the First Stage of an siRNA Amplification Pathway That Targets Recent Gene Duplications

Creator:: Fischer, Sylvia E. J., Montgomery, Taiowa A., Zhang, Chi, Fahlgren, Noah, Breen, Peter C., Hwang, Alexia, Sullivan, Christopher M., Carrington, James C., and Ruvkun, Gary
Abstract:: Endogenous small interfering RNAs (siRNAs) are a class of naturally occuring regulatory RNAs found in fungi, plants, and animals. Some endogenous siRNAs are required to silence transposons or function in chromosome segregation; however, the specific roles of most endogenous siRNAs are unclear. The helicase gene eri-6/7 was identified in the...
Resource Type:: Article
Full Text:: . Sullivan2, James C. Carrington2, Gary Ruvkun1* 1 Department of Molecular Biology, Massachusetts General

Near-Real-Time Acoustic Monitoring of Beaked Whales and Other Cetaceans Using a Seaglider (TM)

Creator:: Klinck, Holger, Mellinger, David K., Klinck, Karolin, Bogue, Neil M., Luby, James C., Jump, William A., Shilling, Geoffrey B., Litchendorf, Trina, Wood, Angela S., Schorr, Gregory S., and Baird, Robin W.
Abstract:: Correction 10 Aug 2012: Klinck H, Mellinger DK, Klinck K, Bogue NM, Luby JC, et al. (2012) Correction: Near-Real-Time Acoustic Monitoring of Beaked Whales and Other Cetaceans Using a Seaglider™. PLOS ONE 7(8): 10.1371/annotation/57ad0b82-87c4-472d-b90b-b9c6f84947f8.
Resource Type:: Article
Full Text:: , Neil M. Bogue2, James C. Luby2, William A. Jump2, Geoffrey B. Shilling2, Trina Litchendorf2, Angela S

High-Density SNP Genotyping of Tomato (Solanum lycopersicum L.) Reveals Patterns of Genetic Variation Due to Breeding

Creator:: Sim, Sung-Chur, Van Deynze, Allen, Stoffel, Kevin, Douches, David S., Zarka, Daniel, Ganal, Martin W., Chetelat, Roger T., Hutton, Samuel F., Scott, John W., Gardner, Randolph G., Panthee, Dilip R., Mutschler, Martha, Myers, James R., and Francis, David M.
Abstract:: The effects of selection on genome variation were investigated and visualized in tomato using a high-density single nucleotide polymorphism (SNP) array. 7,720 SNPs were genotyped on a collection of 426 tomato accessions (410 inbreds and 16 hybrids) and over 97% of the markers were polymorphic in the entire collection. Principal...
Resource Type:: Article
Full Text:: . Hutton6, John W. Scott6, Randolph G. Gardner7, Dilip R. Panthee7, Martha Mutschler8, James R. Myers9

ScholarsArchive@OSU

Uncertainty analysis: an evaluation metric for synthesis science

Footprint of Positive Selection in Treponema pallidum subsp. pallidum Genome Sequences Suggests Adaptive Microevolution of the Syphilis Pathogen

Coibamide A Induces mTOR-Independent Autophagy and Cell Death in Human Glioblastoma Cells

Intra‐ and inter‐annual variation in gray whale body condition on a foraging ground

Genome-Wide Profiling and Analysis of Arabidopsis siRNAs

Genetic and Functional Diversification of Small RNA Pathways in Plants

High-Throughput Sequencing of Arabidopsis microRNAs : Evidence for Frequent Birth and Death of MIRNA Genes

The ERI-6/7 Helicase Acts at the First Stage of an siRNA Amplification Pathway That Targets Recent Gene Duplications

Near-Real-Time Acoustic Monitoring of Beaked Whales and Other Cetaceans Using a Seaglider (TM)

High-Density SNP Genotyping of Tomato (Solanum lycopersicum L.) Reveals Patterns of Genetic Variation Due to Breeding

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