Index Catalog // ScholarsArchive@OSU

Creator:: O’Donnell, Edmond F., Kopparapu, Prasad Rao, Koch, Daniel C., Jang, Hyo Sang, Phillips, Jessica Lynne, Tanguay, Robert L., Kerkvliet, Nancy I., and Kolluri, Siva Kumar
Abstract:: A novel role of the dihydroorotatedehydrogenase (DHODH) inhibitor leflunomide as a potential anti-melanoma therapy was recently reported (Nature 471: 518-22, 2011). We previously reported that leflunomide strongly activates the transcriptional activity of the Aryl Hydrocarbon Receptor (AhR). We therefore tested whether the AhR regulates the anti-proliferative effects of leflunomide in...
Resource Type:: Article
Full Text:: Leflunomide- Induced Growth Inhibition of Melanoma Cells Edmond F. O’Donnell1,2,5, Prasad Rao Kopparapu1,2,5

Creator:: Sim, Sung-Chur, Van Deynze, Allen, Stoffel, Kevin, Douches, David S., Zarka, Daniel, Ganal, Martin W., Chetelat, Roger T., Hutton, Samuel F., Scott, John W., Gardner, Randolph G., Panthee, Dilip R., Mutschler, Martha, Myers, James R., and Francis, David M.
Abstract:: The effects of selection on genome variation were investigated and visualized in tomato using a high-density single nucleotide polymorphism (SNP) array. 7,720 SNPs were genotyped on a collection of 426 tomato accessions (410 inbreds and 16 hybrids) and over 97% of the markers were polymorphic in the entire collection. Principal...
Resource Type:: Article
Full Text:: Deynze2, Kevin Stoffel2, David S. Douches3, Daniel Zarka3, Martin W. Ganal4, Roger T. Chetelat5, Samuel F

Creator:: Mora, Camilo, Wei, Chih-Lin, Rollo, Audrey, Amaro, Teresa, Baco, Amy R., Billett, David, Bopp, Laurent, Chen, Qi, Collier, Mark, Danovaro, Roberto, Gooday, Andrew J., Grupe, Benjamin M., Halloran, Paul R., Ingels, Jeroen, Jones, Daniel O. B., Levin, Lisa A., Nakano, Hideyuki, Norling, Karl, Ramirez-Llodra, Eva, Rex, Michael, Ruhl, Henry A., Smith, Craig R., Sweetman, Andrew K., Thurber, Andrew R., Tjiputra, Jerry F., Usseglio, Paolo, Watling, Les, Wu, Tongwen, and Yasuhara, Moriaki
Abstract:: Ongoing greenhouse gas emissions can modify climate processes and induce shifts in ocean temperature, pH, oxygen concentration, and productivity, which in turn could alter biological and social systems. Here, we provide a synoptic global assessment of the simultaneous changes in future ocean biogeochemical variables over marine biota and their broader...
Resource Type:: Article

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